Interactor 1: CO8A (P07357)
Complement component C8 alpha chain (Complement component 8 subunit alpha)
Gene: C8A
Interactor 2: CO8B (P07358)
Complement component C8 beta chain (Complement component 8 subunit beta)
Gene: C8B
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37343697 |
| Identification Methods | cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C8A_B_C6_EGF-like~MACPF, C8A_B_C6_EGF-like~TSP_1, Ldl_recept_a~Ldl_recept_a, Ldl_recept_a~MACPF, Ldl_recept_a~TSP_1, MACPF~MACPF, MACPF~TSP_1, TSP_1~TSP_1 |
| Common GO terms | GO:0005576 - extracellular region GO:0005579 - membrane attack complex GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0006955 - immune response and 8 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
