Protein: ISR1
Serine/threonine-protein kinase ISR1 (EC 2.7.11.1) (Inhibition of staurosporine resistance protein 1)

Gene: ISR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 41
UniProt ID: Q06098

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0106279 - negative regulation of UDP-N-acetylglucosamine biosynthetic process
GO:0106310 - protein serine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

602642

PHO85
Cyclin-dependent protein kinase PHO85

1

0

Small-scale

0.614

High

676362

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.614

High

800631

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

0

High-throughput

0.614

High

1053585

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

0

High-throughput

0.578

High

667046

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.541

High

748780

YPT7
Ypt/Rab-type GTPase YPT7

1

0

High-throughput

0.541

High

803208

RIM4
Meiotic activator RIM4

1

0

High-throughput

0.541

High

925351

CRZ1
Transcriptional regulator CRZ1

1

0

High-throughput

0.541

High

783511

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

924634

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.513

High

585149

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.480

High

828278

SYA
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.480

High

1053584

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

452053

TOM70
Mitochondrial import receptor subunit TOM70

1

1

High-throughput

0.457

High

585652

STI1
Heat shock protein STI1

1

1

High-throughput

0.457

High

819835

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

571043

CHS2
Chitin synthase 2

2

0

High-throughput

0.330

High

1044002

GIR2
Protein GIR2

1

0

High-throughput

0.282

High

575521

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.279

Low

645539

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.279

Low

793111

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.279

Low

807926

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.279

Low

836615

PTE1
Peroxisomal acyl-coenzyme A thioester hydrolase 1

1

0

High-throughput

0.279

Low

1042837

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

High-throughput

0.279

Low

1043890

NAB6
RNA-binding protein NAB6

1

0

High-throughput

0.279

Low

1053582

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.279

Low

1053583

PBP4
Protein PBP4

1

0

High-throughput

0.279

Low

439593

LEU1
2-isopropylmalate synthase

1

0

High-throughput

0.261

Low

737118

CDC11
Cell division control protein 11

1

0

High-throughput

0.261

Low

781522

YKR18
IML2-like protein YKR018C

1

0

High-throughput

0.261

Low

782308

RNZ
Ribonuclease Z

1

0

High-throughput

0.261

Low

844402

YG4I
Uncharacterized GTP-binding protein YGR210C

1

0

High-throughput

0.261

Low

845900

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

1

0

High-throughput

0.261

Low

849851

BUD27
Bud site selection protein 27

1

0

High-throughput

0.261

Low

866306

YJ9S
Uncharacterized protein YJR154W

1

0

High-throughput

0.261

Low

887762

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.261

Low

1039095

YP077
Uncharacterized protein YPL077C

1

0

High-throughput

0.261

Low

1047502

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.261

Low

460745

CDC4
Cell division control protein 4

1

0

Small-scale

0.249

Low

1046175

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

755175

GCN1
eIF-2-alpha kinase activator GCN1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025