Protein: SCG1
Secretogranin-1 (Chromogranin-B) (CgB) (Secretogranin I) (SgI) [Cleaved into: PE-11; GAWK peptide; CCB peptide]

Gene: SCG1, CHGB
Organism: Homo sapiens
Interactions: 47
UniProt ID: P05060

Gene Ontology (top 5):
GO:0005179 - hormone activity
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0030141 - secretory granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

421165

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

3

5

Small-scale

0.671

High

421163

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

5

High-throughput

0.550

High

240475

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.533

High

421136

S10A8
Protein S100-A8

1

0

High-throughput

0.518

High

421135

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

421143

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.494

High

421150

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

High-throughput

0.494

High

421157

TBB2A
Tubulin beta-2A chain

1

3

High-throughput

0.494

High

421159

SAFB2
Scaffold attachment factor B2

1

2

High-throughput

0.494

High

421174

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

5

High-throughput

0.489

High

405374

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.464

High

421138

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.464

High

421142

ANXA7
Annexin A7

1

1

High-throughput

0.464

High

421151

RAP1B
Ras-related protein Rap-1b

1

2

High-throughput

0.464

High

421161

PKN2
Serine/threonine-protein kinase N2

1

1

High-throughput

0.464

High

421173

UBQL1
Ubiquilin-1

1

1

Small-scale

0.439

High

105107

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

405672

MYCN
N-myc proto-oncogene protein

1

4

High-throughput

0.437

High

421169

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.437

High

421168

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

Small-scale

0.426

High

421139

UBF1
Nucleolar transcription factor 1

1

6

High-throughput

0.417

High

421147

RXRG
Retinoic acid receptor RXR-gamma

1

6

High-throughput

0.417

High

193360

OGG1
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase

1

0

High-throughput

0.282

High

421137

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.282

High

421144

MARK3
MAP/microtubule affinity-regulating kinase 3

1

0

High-throughput

0.282

High

421145

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.282

High

421148

YLPM1
YLP motif-containing protein 1

1

0

High-throughput

0.282

High

421153

ACACA
Acetyl-CoA carboxylase 1

1

0

High-throughput

0.282

High

421156

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.282

High

421158

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.282

High

421162

TAZ
Tafazzin

1

0

High-throughput

0.282

High

421164

CCD92
Coiled-coil domain-containing protein 92

1

0

High-throughput

0.282

High

421166

TWF2
Twinfilin-2

1

0

High-throughput

0.282

High

421167

PRAG1
Inactive tyrosine-protein kinase PRAG1

1

0

High-throughput

0.282

High

421170

MGLL
Monoglyceride lipase

1

0

High-throughput

0.282

High

421171

ATX2
Ataxin-2

1

0

High-throughput

0.282

High

421140

RCC1
Regulator of chromosome condensation

1

0

High-throughput

0.265

Low

421146

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.265

Low

168173

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.249

Low

421149

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.249

Low

421154

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.249

Low

421160

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.249

Low

421141

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.238

Low

421155

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

High-throughput

0.238

Low

421172

Q9H5Q2
HCG1723909

1

0

High-throughput

0.238

Low

404620

PRIO
Major prion protein

1

0

High-throughput

0.232

Low

421152

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025