Protein: PYRD
Dihydroorotate dehydrogenase (fumarate) (DHOD) (DHODase) (DHOdehase) (EC 1.3.98.1) (Dihydroorotate oxidase)

Gene: PYRD, URA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 27
UniProt ID: P28272

Gene Ontology (top 5):
GO:0004152 - dihydroorotate dehydrogenase activity
GO:0005737 - cytoplasm
GO:0006207 - 'de novo' pyrimidine nucleobase biosynthetic process
GO:0044205 - 'de novo' UMP biosynthetic process
GO:1990663 - dihydroorotate dehydrogenase (fumarate) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

701632

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

628043

FKBP
FK506-binding protein 1

1

0

High-throughput

0.513

High

701635

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

701637

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

430795

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

Small-scale

0.458

High

618939

IRA2
Inhibitory regulator protein IRA2

1

0

Small-scale

0.458

High

668247

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.458

High

701626

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

701629

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

701633

GPN1
GPN-loop GTPase 1

1

0

Small-scale

0.458

High

701634

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

701639

ESP1
Separin

1

0

High-throughput

0.458

High

701640

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

High-throughput

0.458

High

701641

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

523254

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526090

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544048

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

701627

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

614802

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

1

High-throughput

0.437

High

701636

RHO4
GTP-binding protein RHO4

1

0

High-throughput

0.279

Low

701631

YEC3
Uncharacterized protein YEL023C

1

0

High-throughput

0.269

Low

701638

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.251

Low

672628

BPH1
Beige protein homolog 1

1

0

High-throughput

0.249

Low

682186

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

701625

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

701628

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

701630

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025