Protein: SRP14
Signal recognition particle subunit SRP14 (Signal recognition particle 14 kDa protein homolog)

Gene: SRP14
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: P38985

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005786 - signal recognition particle, endoplasmic reticulum targeting
GO:0006616 - SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO:0008312 - 7S RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

734821

SRP21
Signal recognition particle subunit SRP21

4

0

High-throughput

0.842

High

713226

SEC65
Signal recognition particle subunit SEC65

6

0

Small-scale

0.702

High

801743

SRP72
Signal recognition particle subunit SRP72

6

0

Small-scale

0.700

High

631923

SRP54
Signal recognition particle subunit SRP54

5

0

High-throughput

0.682

High

801718

SRP68
Signal recognition particle subunit SRP68

4

0

High-throughput

0.661

High

751959

LHP1
La protein homolog

2

0

High-throughput

0.595

High

808480

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

0

High-throughput

0.585

High

444514

DED1
ATP-dependent RNA helicase DED1

1

1

Small-scale

0.561

High

547870

NHP6B
Non-histone chromosomal protein 6B

1

1

Small-scale

0.527

High

793884

PCH2
Pachytene checkpoint protein 2

1

0

High-throughput

0.518

High

798642

SSH1
Sec sixty-one protein homolog

1

0

High-throughput

0.518

High

721934

XPO1
Exportin-1

1

0

High-throughput

0.513

High

808485

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.493

High

547794

NHP6A
Non-histone chromosomal protein 6A

1

1

Small-scale

0.481

High

808481

HRQ1
ATP-dependent helicase HRQ1

1

1

Small-scale

0.479

High

666459

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

707091

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

745739

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

764072

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

808475

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

808479

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

808482

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

523944

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526692

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544867

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

741578

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

808474

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

682277

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.437

High

808477

BRE5
UBP3-associated protein BRE5

2

0

High-throughput

0.318

High

528586

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.282

High

808484

MIM1
Mitochondrial import protein 1

1

0

High-throughput

0.282

High

550579

SST2
Protein SST2

1

0

High-throughput

0.279

Low

579385

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

794985

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

808472

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

808478

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

808483

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

453599

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

752256

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

808473

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.232

Low

808476

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

808486

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025