Protein: SRP21
Signal recognition particle subunit SRP21 (Signal recognition particle 21 kDa protein)

Gene: SRP21
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: P32342

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005786 - signal recognition particle, endoplasmic reticulum targeting
GO:0006614 - SRP-dependent cotranslational protein targeting to membrane
GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

734821

SRP14
Signal recognition particle subunit SRP14

4

0

High-throughput

0.842

High

713214

SEC65
Signal recognition particle subunit SEC65

5

0

Small-scale

0.687

High

734820

SRP72
Signal recognition particle subunit SRP72

5

0

Small-scale

0.676

High

631870

SRP54
Signal recognition particle subunit SRP54

4

0

High-throughput

0.664

High

734819

SRP68
Signal recognition particle subunit SRP68

2

0

High-throughput

0.576

High

721764

XPO1
Exportin-1

1

0

High-throughput

0.513

High

444453

DED1
ATP-dependent RNA helicase DED1

1

1

Small-scale

0.501

High

682200

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.479

High

688977

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

689184

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

734835

HRQ1
ATP-dependent helicase HRQ1

1

1

Small-scale

0.479

High

432518

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.458

High

434534

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.458

High

561434

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

569936

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

600998

RL8A
Large ribosomal subunit protein eL8A

1

0

High-throughput

0.458

High

666414

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

684655

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

706464

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734812

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

734816

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.458

High

734824

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

734828

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.458

High

734829

RL26B
Large ribosomal subunit protein uL24B

1

0

High-throughput

0.458

High

734831

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

734832

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.458

High

734833

NOG1
Nucleolar GTP-binding protein 1

1

0

High-throughput

0.458

High

734834

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

734836

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.458

High

734837

RL11B
Large ribosomal subunit protein uL5B

1

0

High-throughput

0.458

High

481526

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

523329

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

526152

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

544130

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

734813

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

449087

CALM
Calmodulin

1

0

High-throughput

0.269

Low

734815

MYO3
Myosin-3

1

0

High-throughput

0.269

Low

149646

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

383101

RLA4
Large ribosomal subunit protein P2B

1

0

High-throughput

0.249

Low

433988

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.249

Low

481988

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.249

Low

511390

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.249

Low

512316

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

515229

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.249

Low

558635

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

734814

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

734817

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.249

Low

734818

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

734822

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.249

Low

734823

RL34B
Large ribosomal subunit protein eL34B

1

0

High-throughput

0.249

Low

734825

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.249

Low

734826

RL17B
Large ribosomal subunit protein uL22B

1

0

High-throughput

0.249

Low

734830

COPA
Coatomer subunit alpha

1

0

High-throughput

0.249

Low

734827

HLJ1
Protein HLJ1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025