Protein: TIE1
Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)

Gene: TIE1
Organism: Homo sapiens
Interactions: 20
UniProt ID: P35590

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001570 - vasculogenesis
GO:0001701 - in utero embryonic development
GO:0001936 - regulation of endothelial cell proliferation
GO:0003180 - aortic valve morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

582693

EZRI
Ezrin

2

20

High-throughput

0.737

High

773347

PSG5
Pregnancy-specific beta-1-glycoprotein 5

1

16

Small-scale

0.668

High

773356

ANGP4
Angiopoietin-4

1

6

Small-scale

0.647

High

461209

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

468129

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

773344

TIE2
Angiopoietin-1 receptor

1

19

Small-scale

0.618

High

773349

TRIP6
Thyroid receptor-interacting protein 6

2

13

High-throughput

0.606

High

471730

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

20

High-throughput

0.575

High

658995

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

20

High-throughput

0.575

High

773345

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

20

High-throughput

0.575

High

773343

KR108
Keratin-associated protein 10-8

2

13

High-throughput

0.553

High

773355

ZRAN1
Ubiquitin thioesterase ZRANB1

2

5

High-throughput

0.553

High

773350

CDC37
Hsp90 co-chaperone Cdc37

1

20

High-throughput

0.553

High

773348

ANGP1
Angiopoietin-1

1

6

Small-scale

0.527

High

773351

K1C40
Keratin, type I cytoskeletal 40

1

6

High-throughput

0.523

High

773342

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

6

High-throughput

0.515

High

773354

MDFI
MyoD family inhibitor

1

2

High-throughput

0.512

High

773352

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

2

High-throughput

0.494

High

773346

EEA1
Early endosome antigen 1

1

6

High-throughput

0.437

High

773353

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.299

High


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Last updated: 11Aug2025