Interactor 1: TIE1 (P35590)
Tyrosine-protein kinase receptor Tie-1 (EC 2.7.10.1)
Gene: TIE1
Interactor 2: TIE2 (Q02763)
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)
Gene: TEK
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10995770 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | fn3~fn3, PK_Tyr_Ser-Thr~fn3, fn3~ig, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr |
| Common GO terms | GO:0001525 - angiogenesis GO:0004714 - transmembrane receptor protein tyrosine kinase activity GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway and 3 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
