Protein: MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14 (EC 3.1.3.95) (HCV NS5A-transactivated protein 4 splice variant A-binding protein 1) (NS5ATP4ABP1) (Myotubularin-related protein 14) (Phosphatidylinositol-3-phosphate phosphatase) (hJumpy)

Gene: MTMRE, MTMR14
Organism: Homo sapiens
Interactions: 117
UniProt ID: Q8NCE2

Gene Ontology (top 5):
GO:0001726 - ruffle
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005829 - cytosol
GO:0006661 - phosphatidylinositol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1115563

ASPP2
Apoptosis-stimulating of p53 protein 2

2

1

High-throughput

0.633

High

328073

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

1

High-throughput

0.611

High

575167

IDE
Insulin-degrading enzyme

2

0

High-throughput

0.585

High

920122

PLK1
Serine/threonine-protein kinase PLK1

2

0

High-throughput

0.585

High

956755

RAB10
Ras-related protein Rab-10

2

0

High-throughput

0.585

High

1335528

ATX10
Ataxin-10

2

0

High-throughput

0.585

High

1335510

ANM1
Protein arginine N-methyltransferase 1

2

1

High-throughput

0.584

High

1199924

P5CR3
Pyrroline-5-carboxylate reductase 3

2

0

High-throughput

0.559

High

1335506

SEH1
Nucleoporin SEH1

2

0

High-throughput

0.559

High

249490

ACSL4
Long-chain-fatty-acid--CoA ligase 4

2

1

High-throughput

0.558

High

249764

DOK2
Docking protein 2

2

0

High-throughput

0.547

High

631352

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

635735

RASA1
Ras GTPase-activating protein 1

2

0

High-throughput

0.547

High

702360

ELK4
ETS domain-containing protein Elk-4

2

0

High-throughput

0.547

High

711378

SHC1
SHC-transforming protein 1

2

0

High-throughput

0.547

High

717321

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.547

High

905758

CAV2
Caveolin-2

2

0

High-throughput

0.547

High

1143070

KPCD1
Serine/threonine-protein kinase D1

2

0

High-throughput

0.547

High

1144534

PTPRR
Receptor-type tyrosine-protein phosphatase R

2

0

High-throughput

0.547

High

1335527

RHG20
Rho GTPase-activating protein 20

2

0

High-throughput

0.547

High

710863

EPHB2
Ephrin type-B receptor 2

1

2

High-throughput

0.541

High

339539

ACSL3
Fatty acid CoA ligase Acsl3

1

1

High-throughput

0.536

High

837728

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

2

1

High-throughput

0.533

High

564076

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

569023

ENOB
Beta-enolase

1

0

High-throughput

0.518

High

414233

P53
Cellular tumor antigen p53

1

0

High-throughput

0.513

High

1129099

PLSI
Plastin-1

1

0

High-throughput

0.513

High

1310239

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1335515

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

1335525

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.513

High

640225

EPHA1
Ephrin type-A receptor 1

1

2

High-throughput

0.494

High

711915

LTK
Leukocyte tyrosine kinase receptor

1

3

High-throughput

0.494

High

773352

TIE1
Tyrosine-protein kinase receptor Tie-1

1

2

High-throughput

0.494

High

1147381

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.494

High

135660

DNM1L
Dynamin-1-like protein

1

0

High-throughput

0.493

High

422627

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

508289

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

173090

XPO1
Exportin-1

1

1

High-throughput

0.479

High

451628

GPX1
Glutathione peroxidase 1

1

1

High-throughput

0.479

High

788321

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

1

High-throughput

0.479

High

1293373

CARM1
Histone-arginine methyltransferase CARM1

1

1

High-throughput

0.479

High

1335513

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

1

High-throughput

0.479

High

1335514

FN3K
Fructosamine-3-kinase

1

1

High-throughput

0.479

High

1335517

KT3K
Ketosamine-3-kinase

1

1

High-throughput

0.479

High

1053257

Q05BL1
TP53BP2 protein

1

1

High-throughput

0.470

High

51096

PKHG3
Pleckstrin homology domain-containing family G member 3

1

0

High-throughput

0.458

High

162110

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.458

High

217273

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

0

High-throughput

0.458

High

242310

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

319914

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

349163

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.458

High

549201

CDK4
Cyclin-dependent kinase 4

1

0

High-throughput

0.458

High

646891

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.458

High

657913

SYWC
Tryptophan--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

675085

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

703652

MK01
Mitogen-activated protein kinase 1

1

0

High-throughput

0.458

High

717905

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

0

High-throughput

0.458

High

731471

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

831080

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

842980

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

0

High-throughput

0.458

High

934872

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

970795

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1090800

TRAF2
TNF receptor-associated factor 2

1

0

High-throughput

0.458

High

1095418

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

0

High-throughput

0.458

High

1106618

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1112920

CUL2
Cullin-2

1

0

High-throughput

0.458

High

1116252

PTC1
Protein patched homolog 1

1

0

Small-scale

0.458

High

1163892

DUS7
Dual specificity protein phosphatase 7

1

0

High-throughput

0.458

High

1335500

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

0

High-throughput

0.458

High

1335502

FAD1
FAD synthase

1

0

High-throughput

0.458

High

1335503

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

1335507

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

1

0

High-throughput

0.458

High

1335508

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

0

High-throughput

0.458

High

1335512

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1335518

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

1335519

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1335520

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

High-throughput

0.458

High

1335521

ADPPT
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

1

0

High-throughput

0.458

High

1335522

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.458

High

1335523

DCA13
DDB1- and CUL4-associated factor 13

1

0

High-throughput

0.458

High

1335526

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.458

High

1335529

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

1335532

PADI2
Protein-arginine deiminase type-2

1

0

High-throughput

0.458

High

1335530

XPO7
Exportin-7

1

1

High-throughput

0.437

High

530095

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

837405

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

1

High-throughput

0.407

High

1295068

F90A1
Protein FAM90A1

3

0

High-throughput

0.347

High

1334297

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

2

0

High-throughput

0.318

High

228838

SCO2
Protein SCO2 homolog, mitochondrial

2

0

High-throughput

0.305

High

316919

MTA2
Metastasis-associated protein MTA2

2

0

High-throughput

0.298

High

1141439

POSTN
Periostin

1

0

High-throughput

0.279

Low

1199215

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.279

Low

1208225

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

1335505

CHUR
Protein Churchill

1

0

High-throughput

0.279

Low

1335516

WDR54
WD repeat-containing protein 54

1

0

High-throughput

0.279

Low

332323

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.249

Low

341624

EYA4
Protein phosphatase EYA4

1

0

High-throughput

0.249

Low

369709

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.249

Low

589185

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

641809

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

1

0

High-throughput

0.249

Low

660495

ANFC
C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]

1

0

High-throughput

0.249

Low

724135

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.249

Low

773931

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.249

Low

851045

AFAM
Afamin

1

0

High-throughput

0.249

Low

1142331

PDIA6
Protein disulfide-isomerase A6

1

0

High-throughput

0.249

Low

1206101

TGO1
Transport and Golgi organization protein 1 homolog

1

0

High-throughput

0.249

Low

1219929

BSPRY
B box and SPRY domain-containing protein

1

0

High-throughput

0.249

Low

1242297

SFXN4
Sideroflexin-4

1

0

High-throughput

0.249

Low

1254687

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1276225

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

1335501

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

0

High-throughput

0.249

Low

1335504

BPIB1
BPI fold-containing family B member 1

1

0

High-throughput

0.249

Low

1335509

NEB2
Neurabin-2

1

0

High-throughput

0.249

Low

1335511

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

1

0

High-throughput

0.249

Low

1335524

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.249

Low

1335531

ACAD8
Isobutyryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025