Protein: UBA2
Ubiquitin-activating enzyme E1-like (Polymerase-interacting protein 2) (SMT3-activating enzyme subunit 2)

Gene: UBA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 26
UniProt ID: P52488

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016925 - protein sumoylation
GO:0019948 - SUMO activating enzyme activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

912382

RHC31
DNA damage tolerance protein RHC31

7

12

Small-scale

0.970

High

897480

UBC9
SUMO-conjugating enzyme UBC9

6

20

Small-scale

0.950

High

912384

SMT3
Ubiquitin-like protein SMT3

3

10

Small-scale

0.858

High

912375

UBA2
Ubiquitin-activating enzyme E1-like

1

10

Small-scale

0.618

High

524555

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.601

High

912378

UBC7
Ubiquitin-conjugating enzyme E2 7

1

20

High-throughput

0.590

High

712932

PAP
Poly(A) polymerase

2

0

Small-scale

0.575

High

527172

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

545554

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.552

High

819256

SSB2
Ribosome-associated molecular chaperone SSB2

2

7

High-throughput

0.552

High

792871

ANM1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.541

High

741973

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.536

High

912381

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

1

High-throughput

0.536

High

912376

UFD1
Ubiquitin fusion degradation protein 1

1

0

Small-scale

0.529

High

912380

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.513

High

912377

IMB5
Importin subunit beta-5

1

0

Small-scale

0.486

High

912379

ULP1
Ubiquitin-like-specific protease 1

1

2

High-throughput

0.481

High

670926

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

679874

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

707638

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

912383

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

1

High-throughput

0.479

High

594466

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

864780

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

676166

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

752505

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High


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Last updated: 11Aug2025