Protein: PAP
Poly(A) polymerase (PAP) (EC 2.7.7.19) (Polynucleotide adenylyltransferase)

Gene: PAP, PAP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: P29468

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

712928

FIP1
Pre-mRNA polyadenylation factor FIP1

16

5

Small-scale

0.765

High

712936

PTA1
Pre-tRNA-processing protein PTA1

13

2

Small-scale

0.760

High

712916

MPE1
Protein MPE1

8

1

Small-scale

0.750

High

712926

PFS2
Polyadenylation factor subunit 2

8

3

Small-scale

0.748

High

712941

CFT1
Protein CFT1

6

4

Small-scale

0.734

High

712940

YSH1
Endoribonuclease YSH1

6

8

Small-scale

0.732

High

712939

YTH1
mRNA 3'-end-processing protein YTH1

6

4

Small-scale

0.730

High

712943

CFT2
Cleavage factor two protein 2

6

8

Small-scale

0.730

High

712934

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

8

0

Small-scale

0.716

High

712913

PP12
Serine/threonine-protein phosphatase PP1-2

5

1

Small-scale

0.709

High

712925

REF2
RNA end formation protein 2

6

0

Small-scale

0.701

High

712917

SWD2
COMPASS component SWD2

4

3

Small-scale

0.687

High

712923

PTI1
Protein PTI1

5

0

Small-scale

0.684

High

671404

RNA14
mRNA 3'-end-processing protein RNA14

3

1

Small-scale

0.662

High

712921

PCF11
Protein PCF11

3

0

Small-scale

0.634

High

632636

DBP4
ATP-dependent RNA helicase HCA4

2

0

High-throughput

0.595

High

712932

UBA2
Ubiquitin-activating enzyme E1-like

2

0

Small-scale

0.575

High

602352

PHO85
Cyclin-dependent protein kinase PHO85

2

0

Small-scale

0.561

High

712933

UFD1
Ubiquitin fusion degradation protein 1

1

0

Small-scale

0.549

High

544075

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.536

High

712910

XPO1
Exportin-1

1

1

High-throughput

0.536

High

600995

RL8A
Large ribosomal subunit protein eL8A

1

0

High-throughput

0.513

High

712937

IMA1
Importin subunit alpha

1

0

High-throughput

0.513

High

403396

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.480

High

712935

SUB1
RNA polymerase II transcriptional coactivator SUB1

1

0

Small-scale

0.480

High

671441

RNA15
mRNA 3'-end-processing protein RNA15

1

1

Small-scale

0.479

High

392365

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.458

High

594242

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

655613

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.458

High

694493

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

706410

TF2B
Transcription initiation factor IIB

1

0

Small-scale

0.458

High

712911

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

712915

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

712919

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.458

High

712927

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

712930

JHD2
Histone demethylase JHD2

1

0

Small-scale

0.458

High

712942

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

712944

RRP6
Exosome complex exonuclease RRP6

1

0

Small-scale

0.458

High

712945

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

523279

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

526111

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

531644

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

712912

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

712918

PBP2
PAB1-binding protein 2

1

1

High-throughput

0.445

High

712924

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

712931

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

670423

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

712920

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.426

High

712946

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.426

High

712938

NAB6
RNA-binding protein NAB6

2

0

Small-scale

0.323

High

712929

VPS53
Vacuolar protein sorting-associated protein 53

2

0

High-throughput

0.307

High

712922

LAA1
AP-1 accessory protein LAA1

2

0

High-throughput

0.305

High

712914

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025