HitPredict

Interactor 1: H4 (P84040)
Histone H4
Gene: His4

Interactor 2: ISWI (Q24368)
Chromatin-remodeling complex ATPase chain Iswi (EC 3.6.4.-) (CHRAC 140 kDa subunit) (Nucleosome-remodeling factor 140 kDa subunit) (NURF-140) (Protein imitation swi)
Gene: ISWI

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28109157
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 103 Dm			1 1027
+	Hs
		243587 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		SMCA5_HUMAN (24-1027): 0: 958: 71.71
+	Sc
		382398 H4_YEAST (18-103): 5.88e-41: 132: 90.70		ISW2_YEAST (2-1027): 0: 832: 45.46
+	Sc
		382048 H4_YEAST (18-103): 5.88e-41: 132: 90.70		ISW1_YEAST (2-1018): 0: 802: 43.86
+	Hs
		979570 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		CHD3_HUMAN (13-1016): 0: 777: 26.85
+	Hs
		979665 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		CHD4_HUMAN (11-900): 0: 773: 28.36
+	Hs
		160171 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		CHD2_HUMAN (3-1025): 0: 715: 27.53
+	Sp
		152971 H4_SCHPO (18-103): 4.73e-42: 135: 89.54		HRP3_SCHPO (9-1027): 0: 706: 27.72
+	Sc
		381974 H4_YEAST (18-103): 5.88e-41: 132: 90.70		CHD1_YEAST (3-1024): 0: 703: 26.75
+	Sc
		381871 H4_YEAST (18-103): 5.88e-41: 132: 90.70		SNF2_YEAST (7-725): 0: 687: 36.59
+	Hs
		903303 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		SMCA4_HUMAN (64-602): 5.09e-129: 430: 43.81
+	Hs
		979924 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		CHD1L_HUMAN (128-694): 3.29e-132: 423: 42.38
+	Sc
		381968 H4_YEAST (18-103): 5.88e-41: 132: 90.70		STH1_YEAST (9-659): 2.01e-129: 427: 41.31
+	Hs
		980464 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		CHD7_HUMAN (563-1027): 1.73e-21: 103: 11.67
+	Hs
		980029 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		CHD6_HUMAN (600-953): 2.41e-14: 80.2: 12.02
+	Hs
		979752 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		CHD9_HUMAN (793-1016): 2.81e-12: 73.7: 15.77
+	Hs
		980365 H4_HUMAN (1-103): 1.72e-48: 151: 99.03		CHD8_HUMAN (564-1027): 1.72e-11: 71: 13.15