HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: KDM6B (Q5NCY0)
Lysine-specific demethylase 6B (EC 1.14.11.68) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) ([histone H3]-trimethyl-L-lysine(27) demethylase 6B)
Gene: KDM6B

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17825402
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 136 Mm			1 1641
+	Hs
		176053 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KDM6B_HUMAN (1-1641): 0: 715: 90.16
+	Hs
		194544 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KDM6A_HUMAN (1-630): 1.2e-85: 311: 16.69
+	Hs
		194572 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		KDM6A_HUMAN (1-630): 1.2e-85: 311: 16.69
+	Hs
		194577 H32_HUMAN (1-136): 5.34e-59: 180: 97.06		KDM6A_HUMAN (1-630): 1.2e-85: 311: 16.69
+	Hs
		998317 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		MDC1_HUMAN (133-1314): 4.1e-24: 113: 9.43
+	Hs
		1016860 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		MDC1_HUMAN (133-1314): 4.1e-24: 113: 9.43
+	Mm
		107469 H33_MOUSE (1-136): 1.13e-59: 182: 100.00		F8WI37_MOUSE (356-1200): 3.89e-21: 103: 11.52
+	Hs
		998565 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		KMT2C_HUMAN (128-1214): 1.56e-17: 91.8: 10.40
+	Hs
		1017037 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		KMT2C_HUMAN (128-1214): 1.56e-17: 91.8: 10.40
+	Hs
		1161950 H31T_HUMAN (1-136): 2.59e-59: 181: 93.38		KMT2C_HUMAN (128-1214): 1.56e-17: 91.8: 10.40
+	Hs
		1258883 H32_HUMAN (1-136): 5.34e-59: 180: 97.06		KMT2C_HUMAN (128-1214): 1.56e-17: 91.8: 10.40
+	Hs
		999014 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		CABIN_HUMAN (485-931): 4.57e-16: 86.8: 19.00
+	Hs
		1017340 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		CABIN_HUMAN (485-931): 4.57e-16: 86.8: 19.00
+	Hs
		998466 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		SRCAP_HUMAN (104-692): 6.04e-11: 69.9: 9.49
+	Hs
		1016971 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		SRCAP_HUMAN (104-692): 6.04e-11: 69.9: 9.49
+	Hs
		998716 H31_HUMAN (1-136): 3.09e-60: 183: 96.32		MINT_HUMAN (208-1137): 6.34e-09: 63.2: 11.71
+	Hs
		1017146 H33_HUMAN (1-136): 1.13e-59: 182: 100.00		MINT_HUMAN (208-1137): 6.34e-09: 63.2: 11.71
+	Hs
		883586 CENPA_HUMAN (9-133): 2.43e-45: 146: 50.76		ANR11_HUMAN (174-802): 9.14e-14: 79.4: 12.56
+	Sc
		779227 CENPA_YEAST (41-134): 2.79e-31: 112: 67.01		SEC31_YEAST (263-716): 1.51e-12: 75.3: 19.33