HitPredict

Interactor 1: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29656893
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1972 Hs			1 1834
+	Hs
		1056885 MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33		SLX4_HUMAN (1-1834): 0: 1486: 100.00
+	Hs
		1018956 TP53B_HUMAN (1-1972): 0: 766: 100.00		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		1019050 TP53B_HUMAN (1-1972): 0: 766: 100.00		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		1019194 TP53B_HUMAN (1-1972): 0: 766: 100.00		CABIN_HUMAN (880-1364): 9.59e-09: 63.1: 13.91
+	Hs
		1303336 MUC4_HUMAN (32-1771): 6.05e-68: 258: 10.04		MUC4_HUMAN (854-1798): 2.2e-17: 91.7: 9.09
+	Hs
		807793 MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41		PRG4_HUMAN (868-1685): 4.03e-25: 116: 7.07
+	Hs
		801012 MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		801326 MINT_HUMAN (2-1787): 6.67e-46: 185: 7.93		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Hs
		807690 MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41		ANK2_HUMAN (1147-1751): 8.46e-11: 69.7: 10.18
+	Hs
		807791 MAP1B_HUMAN (50-1591): 3.52e-51: 202: 9.41		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		801143 MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33		KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79
+	Dm
		113976 M9PB30_DROME (1064-1755): 2.27e-09: 65.1: 8.65		M9PB30_DROME (1116-1784): 2.28e-27: 124: 8.45
+	Hs
		1056827 MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Hs
		1056910 MDC1_HUMAN (10-773): 2.05e-23: 111: 10.33		CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57
+	Hs
		1056876 MICA3_HUMAN (254-923): 1.94e-14: 81.7: 14.49		MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54
+	Mm
		1351630 PCLO_MOUSE (2-1361): 6.91e-09: 63.7: 8.66		PCLO_MOUSE (826-1830): 1.25e-15: 85.9: 8.22