HitPredict

Interactor 1: DAB1 (P97318)
Disabled homolog 1 (mDab1)
Gene: DAB1

Interactor 2: NCK1 (Q99M51)
SH2/SH3 adapter protein Nck1 (Cytoplasmic protein Nck1) (NCK adapter protein 1) (Nck-1)
Gene: NCK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15110774
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035591 - signaling adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Mm			1 377
+	Mm
		237072 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		NCK2_MOUSE (1-376): 1.08e-94: 289: 67.19
+	Hs
		286343 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		NCK1_HUMAN (1-377): 9.82e-102: 307: 98.94
+	Hs
		221988 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		NCK2_HUMAN (1-376): 8.35e-95: 289: 68.50
+	Hs
		222130 ANS1B_HUMAN (8-229): 3.5e-44: 171: 16.81		NCK2_HUMAN (1-376): 8.35e-95: 289: 68.50
+	Mm
		813510 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		FYN_MOUSE (5-130): 6.14e-22: 99.1: 21.09
+	Mm
		1021151 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		YES_MOUSE (5-152): 5.89e-20: 93.2: 19.74
+	Mm
		431338 DAB1_MOUSE (1-588): 2.09e-86: 281: 100.00		SRC_MOUSE (5-130): 2.56e-17: 85.5: 21.09
+	Hs
		286371 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		ITSN1_HUMAN (1-127): 3.5e-15: 79.6: 15.75
+	Hs
		286400 DAB1_HUMAN (1-588): 1.28e-78: 261: 91.50		SH3K1_HUMAN (7-125): 7.88e-14: 74.7: 19.01
+	Hs
		699913 NUMBL_HUMAN (3-549): 2.09e-53: 193: 14.72		P85A_HUMAN (241-376): 5.72e-21: 96.7: 19.57
+	Dm
		118278 NUMB_DROME (16-521): 6.22e-45: 169: 13.48		M9ND00_DROME (17-267): 3.17e-22: 100: 19.57
+	Rn
		204812 SYNJ1_RAT (96-584): 3.44e-41: 162: 14.42		SRBS2_RAT (3-162): 7.6e-24: 105: 26.83
+	Dm
		1022143 DAB_DROME (2-583): 9.73e-46: 176: 17.93		GRAP_DROME (1-61): 5.12e-17: 80.8: 31.15
+	Rn
		988075 SHC1_RAT (8-354): 7.31e-46: 170: 12.53		GRB2_RAT (3-62): 3.51e-17: 81.3: 28.33
+	Mm
		1296766 ANS1B_MOUSE (8-213): 5.21e-42: 164: 17.06		ITSN1_MOUSE (5-127): 8.56e-17: 84.3: 15.45
+	Mm
		431350 SHC3_MOUSE (9-373): 1.39e-41: 158: 14.43		SRC_MOUSE (5-130): 2.56e-17: 85.5: 21.09
+	Mm
		1022139 DAB2_MOUSE (8-587): 2.67e-40: 158: 25.71		ITSN1_MOUSE (5-127): 8.56e-17: 84.3: 15.45
+	Hs
		1193622 Q49AR9_HUMAN (11-321): 2.27e-43: 165: 15.87		SH3K1_HUMAN (7-125): 7.88e-14: 74.7: 19.01
+	Mm
		1022121 DAB2_MOUSE (8-587): 2.67e-40: 158: 25.71		GRB2_MOUSE (3-62): 3.62e-17: 81.3: 28.33
+	Hs
		1366018 ANS1A_HUMAN (11-241): 4.7e-39: 155: 17.02		SH3K1_HUMAN (7-125): 7.88e-14: 74.7: 19.01