HitPredict

Interactor 1: RAD51 (Q06609)
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
Gene: RAD51

Interactor 2: DMC1 (Q14565)
Meiotic recombination protein DMC1/LIM15 homolog
Gene: DMC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.949

The method score is based on:

Property Details
Experiments 26186194, 10562567, 28514442, 33961781, 15489243, 17541404
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HHH_5~HHH_5, HHH_5~Rad51, Rad51~Rad51
Common GO terms GO:0000150 - DNA strand exchange activity
GO:0000730 - DNA recombinase assembly
GO:0000781 - chromosome, telomeric region
GO:0000794 - condensed nuclear chromosome
GO:0000800 - lateral element
and 14 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 339
Hs

1 340
+ Hs
+ Cl
+ At
+ Sp
+ Hs
+ At
+ Ce
+ Sc
+ Ce
+ Sc
+ Sp
+ At
+ Dm
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024