HitPredict

Interactor 1: Q49AR9 (Q49AR9)
ANKS1A protein
Gene: ANKS1A

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 570 Hs			1 665
+	Hs
		1366018 ANS1A_HUMAN (1-493): 8.72e-149: 458: 92.90		SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00
+	Hs
		1366054 ANS1A_HUMAN (1-493): 8.72e-149: 458: 92.90		CD2AP_HUMAN (1-664): 1.84e-95: 309: 32.36
+	Hs
		1280000 ANS1B_HUMAN (1-437): 4.44e-140: 438: 57.43		CD2AP_HUMAN (1-664): 1.84e-95: 309: 32.36
+	Hs
		1127348 Q49AR9_HUMAN (1-570): 0: 574: 100.00		CASL_HUMAN (2-656): 2.59e-38: 154: 11.91
+	Hs
		250255 Q49AR9_HUMAN (1-570): 0: 574: 100.00		VINEX_HUMAN (67-445): 6.54e-15: 80.5: 19.82
+	Hs
		1127362 ANS1A_HUMAN (1-493): 8.72e-149: 458: 92.90		CASL_HUMAN (2-656): 2.59e-38: 154: 11.91
+	Hs
		1360325 CSKI2_HUMAN (5-256): 2.19e-52: 195: 21.45		SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00
+	Hs
		250305 ANS1A_HUMAN (1-493): 8.72e-149: 458: 92.90		VINEX_HUMAN (67-445): 6.54e-15: 80.5: 19.82
+	Hs
		222130 ANS1B_HUMAN (1-437): 4.44e-140: 438: 57.43		NCK2_HUMAN (244-432): 3.03e-17: 86.2: 21.24
+	Mm
		1296766 ANS1B_MOUSE (1-497): 3.94e-137: 430: 52.65		ITSN1_MOUSE (120-423): 3.69e-18: 91.6: 15.24
+	Mm
		1296751 ANS1B_MOUSE (1-497): 3.94e-137: 430: 52.65		ARHG7_MOUSE (222-362): 1.04e-11: 70.4: 19.15
+	Hs
		987727 SH2D5_HUMAN (270-570): 1.81e-56: 197: 17.16		GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37
+	Mm
		1022218 SHC1_MOUSE (146-570): 1.17e-53: 193: 13.92		GRB2_MOUSE (2-158): 8.55e-35: 133: 20.37
+	Mm
		1021161 DAB1_MOUSE (232-533): 1.06e-55: 199: 16.25		NCK1_MOUSE (104-413): 1.87e-26: 113: 16.92
+	Hs
		594061 CSKI2_HUMAN (5-256): 2.19e-52: 195: 21.45		NCK1_HUMAN (104-413): 3.74e-26: 112: 16.62
+	Ce
		711465 Q93203_CAEEL (97-411): 1.34e-52: 195: 20.00		SEM5_CAEEL (4-70): 2.01e-20: 92.7: 35.82
+	Mm
		237072 DAB1_MOUSE (232-533): 1.06e-55: 199: 16.25		NCK2_MOUSE (244-432): 4.01e-16: 82.8: 22.28
+	Hs
		222165 CSKI2_HUMAN (5-256): 2.19e-52: 195: 21.45		NCK2_HUMAN (244-432): 3.03e-17: 86.2: 21.24
+	Mm
		313431 SHC1_MOUSE (146-570): 1.17e-53: 193: 13.92		GRAP2_MOUSE (1-58): 1.39e-16: 83.2: 29.31
+	Ce
		1372518 Q93203_CAEEL (97-411): 1.34e-52: 195: 20.00		Q9U2T9_CAEEL (142-349): 1.51e-13: 76.5: 18.48