HitPredict

Interactor 1: DAB2 (P98078)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)
Gene: DAB2

Interactor 2: NOSTN (Q6WKZ7)
Nostrin (Disabled homolog 2-interacting protein 2) (Dab2-interacting protein 2) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer)
Gene: Nostrin

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	0.60	0.506

Property	Details
Experiments	15596140
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 766 Mm			1 506
+	Hs
		155657 DAB2_HUMAN (1-766): 9.44e-78: 267: 81.63		FCHO1_HUMAN (10-431): 1.06e-43: 167: 16.75
+	Hs
		1022154 DAB2_HUMAN (1-766): 9.44e-78: 267: 81.63		FCHO2_HUMAN (10-427): 4.79e-40: 156: 16.82
+	Mm
		1022139 DAB2_MOUSE (1-766): 2.91e-93: 309: 100.00		ITSN1_MOUSE (421-494): 1.21e-14: 79.1: 31.08
+	Mm
		1022132 DAB2_MOUSE (1-766): 2.91e-93: 309: 100.00		SH3K1_MOUSE (447-495): 2.57e-12: 71.4: 40.82
+	Mm
		1223181 ANS1B_MOUSE (2-243): 4.98e-43: 170: 17.89		PACN1_MOUSE (3-495): 2.88e-51: 182: 17.13
+	Hs
		1022189 DAB2_HUMAN (1-766): 9.44e-78: 267: 81.63		SH3K1_HUMAN (447-495): 1.95e-12: 71.8: 42.86
+	Hs
		1022168 DAB2_HUMAN (1-766): 9.44e-78: 267: 81.63		ITSN1_HUMAN (321-504): 3.32e-09: 61.7: 16.58
+	Mm
		1224164 ANS1B_MOUSE (2-243): 4.98e-43: 170: 17.89		SH3G2_MOUSE (131-495): 8.23e-39: 146: 18.16
+	Hs
		250305 ANS1A_HUMAN (1-248): 1.52e-34: 144: 19.44		VINEX_HUMAN (354-499): 6.46e-30: 125: 26.12
+	Hs
		250255 Q49AR9_HUMAN (1-285): 2.51e-35: 143: 17.65		VINEX_HUMAN (354-499): 6.46e-30: 125: 26.12
+	Mm
		1296766 ANS1B_MOUSE (2-243): 4.98e-43: 170: 17.89		ITSN1_MOUSE (421-494): 1.21e-14: 79.1: 31.08
+	Hs
		286400 DAB1_HUMAN (11-633): 9.61e-39: 154: 22.95		SH3K1_HUMAN (447-495): 1.95e-12: 71.8: 42.86
+	Hs
		571698 PCLO_HUMAN (182-751): 4.43e-09: 62.6: 9.83		HCLS1_HUMAN (48-496): 9.12e-43: 160: 12.77
+	Hs
		319232 ANS1A_HUMAN (1-248): 1.52e-34: 144: 19.44		FCSD2_HUMAN (22-504): 5.42e-14: 76.8: 12.88
+	Hs
		319216 Q49AR9_HUMAN (1-285): 2.51e-35: 143: 17.65		FCSD2_HUMAN (22-504): 5.42e-14: 76.8: 12.88
+	Hs
		1366018 ANS1A_HUMAN (1-248): 1.52e-34: 144: 19.44		SH3K1_HUMAN (447-495): 1.95e-12: 71.8: 42.86
+	Hs
		286371 DAB1_HUMAN (11-633): 9.61e-39: 154: 22.95		ITSN1_HUMAN (321-504): 3.32e-09: 61.7: 16.58
+	Hs
		1193622 Q49AR9_HUMAN (1-285): 2.51e-35: 143: 17.65		SH3K1_HUMAN (447-495): 1.95e-12: 71.8: 42.86