Protein: RPC5
DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide)

Gene: RPC5, POLR3E
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q9NVU0

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex
GO:0005829 - cytosol
GO:0042797 - tRNA transcription by RNA polymerase III
GO:0045087 - innate immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

402756

RPC4
DNA-directed RNA polymerase III subunit RPC4

7

4

Small-scale

0.970

High

1346856

RPC2
DNA-directed RNA polymerase III subunit RPC2

6

3

Small-scale

0.949

High

169969

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

5

3

High-throughput

0.932

High

1346867

RPC10
DNA-directed RNA polymerase III subunit RPC10

5

3

High-throughput

0.932

High

1328662

RPC6
DNA-directed RNA polymerase III subunit RPC6

4

1

High-throughput

0.909

High

921177

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

1

High-throughput

0.861

High

156072

RPC1
DNA-directed RNA polymerase III subunit RPC1

6

3

Small-scale

0.738

High

1346869

RPC8
DNA-directed RNA polymerase III subunit RPC8

6

2

High-throughput

0.736

High

583819

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

5

1

High-throughput

0.725

High

270230

RPC9
DNA-directed RNA polymerase III subunit RPC9

5

1

High-throughput

0.722

High

175541

RPC7
DNA-directed RNA polymerase III subunit RPC7

5

2

Small-scale

0.718

High

1311824

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

4

2

High-throughput

0.704

High

1312890

RPC3
DNA-directed RNA polymerase III subunit RPC3

4

1

High-throughput

0.704

High

897644

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

1

High-throughput

0.699

High

738076

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

3

1

High-throughput

0.667

High

865002

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

3

1

High-throughput

0.667

High

906160

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

3

1

High-throughput

0.667

High

1336397

GPN1
GPN-loop GTPase 1

3

1

High-throughput

0.667

High

295682

RMP
Unconventional prefoldin RPB5 interactor 1

4

0

Small-scale

0.664

High

854379

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

2

High-throughput

0.656

High

1346864

GPN3
GPN-loop GTPase 3

4

1

High-throughput

0.638

High

1332504

RPAP3
RNA polymerase II-associated protein 3

3

0

High-throughput

0.638

High

1346860

UXT
Protein UXT

3

0

High-throughput

0.638

High

61767

BDP1
Transcription factor TFIIIB component B'' homolog

2

1

High-throughput

0.628

High

213777

MCAT
Mitochondrial carnitine/acylcarnitine carrier protein

2

2

High-throughput

0.628

High

1327198

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

2

1

High-throughput

0.628

High

583601

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.618

High

677027

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

3

High-throughput

0.618

High

738895

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

3

High-throughput

0.618

High

1334513

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

3

High-throughput

0.618

High

1242182

GIMA8
GTPase IMAP family member 8

2

0

High-throughput

0.602

High

1346870

TF3C3
General transcription factor 3C polypeptide 3

2

0

High-throughput

0.602

High

1346863

PFD2
Prefoldin subunit 2

2

0

High-throughput

0.585

High

309919

UCP5
Brain mitochondrial carrier protein 1

2

1

High-throughput

0.574

High

1173772

ACD11
Acyl-CoA dehydrogenase family member 11

2

1

High-throughput

0.574

High

1221375

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

0

High-throughput

0.559

High

484488

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

2

2

High-throughput

0.552

High

587017

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.536

High

934512

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

996928

SSRP1
FACT complex subunit SSRP1

1

2

Small-scale

0.536

High

1273560

TF3B
Transcription factor IIIB 90 kDa subunit

1

2

High-throughput

0.536

High

314783

PSMG1
Proteasome assembly chaperone 1

1

0

High-throughput

0.513

High

314896

FMNL1
Formin-like protein 1

1

0

High-throughput

0.513

High

446809

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

671028

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

0

High-throughput

0.513

High

799384

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.513

High

856250

HXK2
Hexokinase-2

1

0

High-throughput

0.513

High

921750

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.513

High

933638

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

986858

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1049339

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.513

High

1182963

SPT6H
Transcription elongation factor SPT6

1

0

High-throughput

0.513

High

1203677

AROS
Active regulator of SIRT1

1

0

High-throughput

0.513

High

1283598

TRI52
E3 ubiquitin-protein ligase TRIM52

1

0

High-throughput

0.513

High

1346865

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.513

High

1346866

RUVB2
RuvB-like 2

1

0

High-throughput

0.513

High

1346868

TPRKB
EKC/KEOPS complex subunit TPRKB

1

0

High-throughput

0.513

High

809453

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.493

High

518506

ADT3
ADP/ATP translocase 3

1

1

High-throughput

0.489

High

1335670

TPC
Mitochondrial thiamine pyrophosphate carrier

1

2

High-throughput

0.489

High

317168

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

3

High-throughput

0.479

High

625065

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

High-throughput

0.479

High

854482

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

2

High-throughput

0.479

High

913965

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

2

High-throughput

0.479

High

918024

H4
Histone H4

1

1

High-throughput

0.479

High

986995

SUH
Recombining binding protein suppressor of hairless

1

1

High-throughput

0.479

High

1137961

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

2

High-throughput

0.479

High

1299005

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

2

High-throughput

0.479

High

1343453

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

2

High-throughput

0.479

High

1346858

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

3

High-throughput

0.479

High

179850

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

181468

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

High-throughput

0.458

High

228866

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

553864

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

575602

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

622623

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.458

High

943906

RAE1L
mRNA export factor RAE1

1

0

High-throughput

0.458

High

1300961

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1326433

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1342919

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

1346861

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1346862

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

87446

C9JLU1
RNA polymerase II, I and III subunit H

1

2

High-throughput

0.445

High

90013

D6R9U7
RNA polymerase III subunit G

1

2

High-throughput

0.445

High

484418

RPC22
Protein POLR1D, isoform 2

1

0

High-throughput

0.426

High

1233229

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

1303796

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.426

High

1346857

PIHD1
PIH1 domain-containing protein 1

5

0

High-throughput

0.374

High

1298308

DAA10
Dynein axonemal assembly factor 10

3

0

High-throughput

0.347

High

398446

CP2E1
Cytochrome P450 2E1

2

0

High-throughput

0.328

High

171685

PFD6
Prefoldin subunit 6

2

0

High-throughput

0.318

High

1345922

PDRG1
p53 and DNA damage-regulated protein 1

2

0

High-throughput

0.318

High

363393

RET4
Retinol-binding protein 4

1

0

High-throughput

0.279

Low

440765

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.279

Low

507649

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1187613

TRM1L
TRMT1-like protein

1

0

High-throughput

0.279

Low

1260159

TM263
Transmembrane protein 263

1

0

High-throughput

0.279

Low

1262669

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.279

Low

1346859

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.279

Low

1150704

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

1171957

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1331433

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024