HitPredict

Interactor 1: NFX1 (Q12986)
Transcriptional repressor NF-X1 (EC 2.3.2.-) (Nuclear transcription factor, X box-binding protein 1)
Gene: NFX1

Interactor 2: YTDC2 (Q9H6S0)
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)
Gene: YTHDC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31059266
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	R3H~R3H
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1120 Hs			1 1430
+	Hs
		1022206 NFX1_HUMAN (1-1120): 0: 740: 100.00		DHX36_HUMAN (71-521): 4.15e-100: 346: 27.63
+	Hs
		1022134 NFX1_HUMAN (1-1120): 0: 740: 100.00		DHX29_HUMAN (139-425): 6.43e-94: 334: 39.32
+	Hs
		994137 NFX1_HUMAN (1-1120): 0: 740: 100.00		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Hs
		1022122 NFX1_HUMAN (1-1120): 0: 740: 100.00		DHX57_HUMAN (155-408): 6.08e-60: 229: 49.23
+	Hs
		1022131 NFX1_HUMAN (1-1120): 0: 740: 100.00		DHX30_HUMAN (163-405): 4.25e-41: 167: 39.39
+	Hs
		804244 NOTC1_HUMAN (309-636): 5.92e-15: 82.7: 11.54		DHX8_HUMAN (25-482): 1.24e-127: 428: 22.61
+	Dm
		246815 TENM_DROME (794-1005): 4.51e-20: 99.2: 11.06		DHX15_DROME (164-482): 1.08e-111: 371: 26.13
+	Hs
		195367 NOTC1_HUMAN (309-636): 5.92e-15: 82.7: 11.54		DHX15_HUMAN (164-482): 6.33e-112: 374: 26.65
+	Hs
		994239 FRAS1_HUMAN (537-963): 2.12e-14: 80.7: 11.78		DHX9_HUMAN (119-458): 1.05e-90: 323: 32.77
+	Dm
		247227 TENM_DROME (794-1005): 4.51e-20: 99.2: 11.06		Q9VX63_DROME (15-415): 1.24e-54: 209: 32.84