HitPredict

Interactor 1: NR1H3 (Q13133)
Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear receptor subfamily 1 group H member 3)
Gene: NR1H3

Interactor 2: DDI2 (Q5TDH0)
Protein DDI1 homolog 2 (EC 3.4.23.-)
Gene: DDI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 447 Hs			1 399
+	Hs
		587200 RXRA_HUMAN (6-445): 5.73e-129: 382: 22.89		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Hs
		94002 F1D8P7_HUMAN (12-447): 3.72e-124: 370: 62.04		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		370703 ESR1_HUMAN (6-446): 3.36e-116: 354: 20.04		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		488035 RARA_HUMAN (15-447): 1.17e-111: 338: 29.00		UBQL1_HUMAN (5-241): 5.78e-49: 176: 14.80
+	Hs
		803455 NR1H2_HUMAN (12-447): 3.47e-127: 377: 61.96		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Hs
		1269715 ESR2_HUMAN (2-446): 1.53e-101: 314: 19.69		UBQL4_HUMAN (8-241): 1.8e-44: 164: 14.59
+	Mm
		509349 RARA_MOUSE (15-447): 9.18e-112: 338: 29.00		NRIP2_MOUSE (197-396): 6.53e-30: 118: 17.87
+	Hs
		803676 ESR2_HUMAN (2-446): 1.53e-101: 314: 19.69		BAG6_HUMAN (4-173): 4.8e-28: 118: 15.08
+	Mm
		740803 THB_MOUSE (39-444): 5.97e-102: 313: 29.26		NRIP2_MOUSE (197-396): 6.53e-30: 118: 17.87
+	Hs
		872148 PPARA_HUMAN (5-443): 6.93e-102: 313: 25.43		RD23A_HUMAN (3-198): 2.36e-28: 116: 15.00
+	Hs
		369351 ESR1_HUMAN (6-446): 3.36e-116: 354: 20.04		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Hs
		320199 ERR2_HUMAN (9-446): 3.62e-117: 351: 25.23		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Hs
		487936 RARA_HUMAN (15-447): 1.17e-111: 338: 29.00		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06
+	Hs
		924098 ESR2_HUMAN (2-446): 1.53e-101: 314: 19.69		RS27A_HUMAN (10-77): 3.2e-14: 71.7: 22.06