HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.895

Property	Details
Experiments	29845934, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 582
+	Hs
		1116304 PAP1L_HUMAN (1-272): 4.36e-38: 143: 14.59		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1031352 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		516541 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1031314 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516502 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		1040370 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		403212 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		516339 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		516495 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		474022 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		1040382 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		1031407 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Hs
		474021 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		1119141 PAP1L_HUMAN (1-272): 4.36e-38: 143: 14.59		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Mm
		665745 PABP1_MOUSE (1-267): 1.23e-37: 142: 13.77		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Hs
		1040345 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1031367 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		516561 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1031344 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50