HitPredict

Interactor 1: F5GZI3 (F5GZI3)
Partitioning defective 3 homolog (Atypical PKC isotype-specific-interacting protein)
Gene: PARD3

Interactor 2: PAR6A (Q9NPB6)
Partitioning defective 6 homolog alpha (PAR-6) (PAR-6 alpha) (PAR-6A) (PAR6C) (Tax interaction protein 40) (TIP-40)
Gene: PARD6A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 747 Hs			1 346
+	Hs
		104041 F5GZI3_HUMAN (1-747): 1.08e-139: 430: 100.00		PAR6B_HUMAN (1-322): 2.8e-95: 289: 50.59
+	Mm
		1408943 PARD3_MOUSE (1-747): 1.58e-120: 394: 86.71		PAR6A_MOUSE (1-346): 1.43e-106: 317: 93.06
+	Hs
		1353284 PARD3_HUMAN (1-747): 8.1e-120: 392: 95.16		PAR6A_HUMAN (1-346): 1.2e-106: 317: 100.00
+	Hs
		1353263 PARD3_HUMAN (1-747): 8.1e-120: 392: 95.16		PAR6B_HUMAN (1-322): 2.8e-95: 289: 50.59
+	Mm
		1408940 PARD3_MOUSE (1-747): 1.58e-120: 394: 86.71		PAR6B_MOUSE (1-333): 1.55e-93: 284: 51.15
+	Hs
		1353262 PARD3_HUMAN (1-747): 8.1e-120: 392: 95.16		PAR6G_HUMAN (12-332): 1.16e-85: 265: 52.82
+	Hs
		168727 PAR3L_HUMAN (1-739): 1.7e-81: 284: 39.50		CSKP_HUMAN (25-344): 3.12e-63: 218: 18.99
+	Hs
		168680 DLG1_HUMAN (3-502): 2.01e-44: 174: 14.92		CSKP_HUMAN (25-344): 3.12e-63: 218: 18.99
+	Mm
		267274 DLG1_MOUSE (3-502): 1.47e-42: 168: 15.19		CSKP_MOUSE (25-344): 3.21e-63: 217: 18.99
+	Rn
		1224257 DLG1_RAT (3-502): 3.2e-42: 167: 15.34		CSKP_RAT (25-344): 2.24e-57: 201: 17.88
+	Hs
		1091491 DLG1_HUMAN (3-502): 2.01e-44: 174: 14.92		MPP2_HUMAN (26-344): 1.07e-51: 182: 16.51
+	Rn
		313210 DLG1_RAT (3-502): 3.2e-42: 167: 15.34		MPP3_RAT (51-327): 2.62e-46: 167: 19.66
+	Mm
		1190725 Q3UP61_MOUSE (3-502): 1.15e-44: 174: 14.84		DLG4_MOUSE (115-252): 6.02e-22: 98.9: 21.01
+	Hs
		1091503 DLG1_HUMAN (3-502): 2.01e-44: 174: 14.92		DLG2_HUMAN (107-250): 2.41e-21: 97.3: 21.38
+	Mm
		1223689 DLG2_MOUSE (3-612): 5.07e-44: 172: 13.58		DLG4_MOUSE (115-252): 6.02e-22: 98.9: 21.01
+	Ce
		111226 DLG1_CAEEL (69-696): 1.69e-45: 177: 18.46		Q17549_CAEEL (169-287): 3.18e-20: 93.8: 21.77
+	Mm
		1223608 DLG1_MOUSE (3-502): 1.47e-42: 168: 15.19		DLG4_MOUSE (115-252): 6.02e-22: 98.9: 21.01
+	Rn
		723883 DLG1_RAT (3-502): 3.2e-42: 167: 15.34		DLG4_RAT (115-252): 5.49e-22: 98.9: 21.01
+	Hs
		1091548 DLG1_HUMAN (3-502): 2.01e-44: 174: 14.92		DLG3_HUMAN (159-239): 3.04e-17: 85: 27.16
+	Mm
		999796 DLG2_MOUSE (3-612): 5.07e-44: 172: 13.58		DLG3_MOUSE (138-239): 9.35e-18: 86.5: 22.55