HitPredict

Interactor 1: F5GZI3 (F5GZI3)
Partitioning defective 3 homolog (Atypical PKC isotype-specific-interacting protein)
Gene: PARD3

Interactor 2: PAR6B (Q9BYG5)
Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B)
Gene: PARD6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 747 Hs			1 372
+	Mm
		1408940 PARD3_MOUSE (1-747): 1.58e-120: 394: 86.71		PAR6B_MOUSE (1-372): 9.53e-160: 454: 91.40
+	Hs
		1353263 PARD3_HUMAN (1-747): 8.1e-120: 392: 95.16		PAR6B_HUMAN (1-372): 5.97e-157: 447: 100.00
+	Hs
		1353262 PARD3_HUMAN (1-747): 8.1e-120: 392: 95.16		PAR6G_HUMAN (1-372): 1.48e-130: 380: 54.73
+	Hs
		104042 F5GZI3_HUMAN (1-747): 1.08e-139: 430: 100.00		PAR6A_HUMAN (1-325): 1.85e-96: 292: 53.37
+	Mm
		1408943 PARD3_MOUSE (1-747): 1.58e-120: 394: 86.71		PAR6A_MOUSE (1-330): 1.48e-100: 303: 52.07
+	Hs
		1353284 PARD3_HUMAN (1-747): 8.1e-120: 392: 95.16		PAR6A_HUMAN (1-325): 1.85e-96: 292: 53.37
+	Hs
		168727 PAR3L_HUMAN (1-739): 1.7e-81: 284: 39.50		CSKP_HUMAN (71-307): 1.1e-57: 203: 19.61
+	Dm
		356505 Q0KHR3_DROME (300-401): 1.18e-20: 99.8: 50.00		O97111_DROME (7-297): 6.12e-95: 289: 53.74
+	Dm
		356518 Q9VX75_DROME (300-401): 1.16e-20: 99.8: 50.00		O97111_DROME (7-297): 6.12e-95: 289: 53.74
+	Dm
		356520 X2JFU8_DROME (300-401): 1.23e-20: 99.8: 50.00		O97111_DROME (7-297): 6.12e-95: 289: 53.74
+	Hs
		168680 DLG1_HUMAN (3-502): 2.01e-44: 174: 14.92		CSKP_HUMAN (71-307): 1.1e-57: 203: 19.61
+	Mm
		267274 DLG1_MOUSE (3-502): 1.47e-42: 168: 15.19		CSKP_MOUSE (71-307): 1.17e-57: 203: 19.61
+	Rn
		1224257 DLG1_RAT (3-502): 3.2e-42: 167: 15.34		CSKP_RAT (71-307): 7.58e-57: 200: 19.75
+	Ce
		111226 DLG1_CAEEL (69-696): 1.69e-45: 177: 18.46		Q17549_CAEEL (74-298): 3.82e-41: 155: 16.74
+	Hs
		1091491 DLG1_HUMAN (3-502): 2.01e-44: 174: 14.92		MPP2_HUMAN (69-305): 6.08e-38: 145: 15.19
+	Rn
		313210 DLG1_RAT (3-502): 3.2e-42: 167: 15.34		MPP3_RAT (72-358): 1.84e-40: 152: 17.35
+	Hs
		168730 DLG3_HUMAN (3-93): 2.09e-20: 98.4: 15.05		CSKP_HUMAN (71-307): 1.1e-57: 203: 19.61
+	Hs
		299772 MPDZ_HUMAN (3-86): 9.16e-24: 109: 19.05		PALS1_HUMAN (82-306): 6.44e-37: 143: 20.00
+	Mm
		1223777 DLG4_MOUSE (3-122): 1.11e-17: 89.8: 21.67		MPP2_MOUSE (68-305): 3.08e-37: 143: 15.13
+	Dm
		122382 Q0KHR3_DROME (300-401): 1.18e-20: 99.8: 50.00		M9PJD0_DROME (131-306): 2.59e-33: 133: 24.16