HitPredict

Interactor 1: LAMB3 (Q13751)
Laminin subunit beta-3 (Epiligrin subunit bata) (Kalinin B1 chain) (Kalinin subunit beta) (Laminin B1k chain) (Laminin-5 subunit beta) (Nicein subunit beta)
Gene: LAMB3

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	32409323, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1172 Hs			1 293
+	Hs
		1045109 LAMB3_HUMAN (1-1172): 0: 643: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		877456 LAMB2_HUMAN (449-748): 1.04e-15: 84.9: 14.54		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		433191 LAMB1_HUMAN (449-693): 3.08e-14: 80.3: 13.65		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		172709 LAMA5_HUMAN (152-326): 1.32e-12: 74.9: 15.51		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		502876 LAMC1_HUMAN (143-379): 5.36e-12: 72.6: 14.35		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1087532 LAMA3_HUMAN (528-684): 3.24e-10: 67.2: 11.95		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		980571 NOTC2_HUMAN (255-723): 8.86e-43: 173: 15.05		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1081784 LAMA4_HUMAN (196-413): 9.66e-32: 137: 24.07		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1356263 LAMC3_HUMAN (430-664): 6.06e-20: 98.8: 19.28		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		631086 LAMA1_HUMAN (151-358): 3.34e-17: 89.9: 16.74		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		877461 LAMB2_HUMAN (449-748): 1.04e-15: 84.9: 14.54		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		433202 LAMB1_HUMAN (449-693): 3.08e-14: 80.3: 13.65		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		172717 LAMA5_HUMAN (152-326): 1.32e-12: 74.9: 15.51		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		502885 LAMC1_HUMAN (143-379): 5.36e-12: 72.6: 14.35		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		804367 NOTC1_HUMAN (432-707): 5.63e-11: 69.5: 13.84		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1087533 LAMA3_HUMAN (528-684): 3.24e-10: 67.2: 11.95		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17