HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.692

The method score is based on:

Property Details
Experiments 33438746, 11684013, 21131967, 12881425
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006954 - inflammatory response
GO:0035556 - intracellular signal transduction
GO:0043066 - negative regulation of apoptotic process
and 2 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 551
Hs

1 592
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
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+ Rn

Service provided by Combinatics, Japan

Last updated: 11Aug2025