HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: PKN3 (Q6P5Z2)
Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3)
Gene: PKN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33438746
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0035556 - intracellular signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 889
+	Hs
		603244 TF65_HUMAN (1-551): 0: 601: 100.00		KPCA_HUMAN (383-889): 1.62e-168: 507: 34.56
+	Hs
		666236 TF65_HUMAN (1-551): 0: 601: 100.00		KPCL_HUMAN (522-886): 1.08e-151: 464: 41.96
+	Hs
		1045197 TF65_HUMAN (1-551): 0: 601: 100.00		KPCT_HUMAN (468-884): 5.16e-149: 457: 37.68
+	Rn
		432383 NFKB1_RAT (7-451): 3.67e-154: 467: 30.06		KPCA_RAT (383-889): 1.2e-168: 507: 34.17
+	Hs
		728580 REL_HUMAN (12-523): 3.58e-165: 484: 41.64		AKT2_HUMAN (494-883): 2.12e-155: 466: 38.99
+	Rn
		866340 NFKB1_RAT (7-451): 3.67e-154: 467: 30.06		AKT1_RAT (494-883): 3.04e-154: 463: 38.48
+	Hs
		287689 TF65_HUMAN (1-551): 0: 601: 100.00		KS6A5_HUMAN (429-815): 7.7e-96: 320: 21.39
+	Hs
		1045204 TF65_HUMAN (1-551): 0: 601: 100.00		KPCD_HUMAN (564-886): 1.3e-90: 303: 48.31
+	Hs
		287656 NFKB1_HUMAN (7-451): 2.24e-153: 465: 29.51		KS6A5_HUMAN (429-815): 7.7e-96: 320: 21.39
+	Hs
		340827 NFAC1_HUMAN (1-503): 2.81e-93: 307: 18.89		KS6B1_HUMAN (521-888): 1.34e-151: 458: 37.60
+	Hs
		1045336 TF65_HUMAN (1-551): 0: 601: 100.00		PKN2_HUMAN (64-261): 2.74e-10: 66.6: 23.74