HitPredict

Interactor 1: TIP13 (O82598)
Aquaporin TIP1-3 (Gamma-tonoplast intrinsic protein 3) (Gamma-TIP3) (Tonoplast intrinsic protein 1-3) (AtTIP1;3)
Gene: TIP1-3

Interactor 2: TIP22 (Q41975)
Probable aquaporin TIP2-2 (Tonoplast intrinsic protein 2-2) (AtTIP2;2)
Gene: TIP2-2

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	24833385
Identification Methods	protein complementation assay, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	MIP~MIP
Common GO terms	GO:0015250 - water channel activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 252 At			1 250
+	At
		794929 PIP22_ARATH (7-245): 6.2e-84: 253: 32.02		PIP14_ARATH (9-245): 4.13e-84: 254: 31.98
+	At
		794924 PIP22_ARATH (7-245): 6.2e-84: 253: 32.02		PIP27_ARATH (9-243): 5.63e-84: 253: 34.29
+	At
		794680 PIP22_ARATH (7-245): 6.2e-84: 253: 32.02		PIP21_ARATH (10-243): 2.81e-83: 252: 31.45
+	At
		794926 PIP22_ARATH (7-245): 6.2e-84: 253: 32.02		PIP13_ARATH (10-245): 3.99e-83: 251: 31.71
+	Hs
		876218 AQP4_HUMAN (14-252): 4.36e-82: 250: 33.06		AQP4_HUMAN (12-241): 1.24e-83: 254: 37.34
+	At
		794925 PIP22_ARATH (7-245): 6.2e-84: 253: 32.02		PIP12_ARATH (9-245): 1.03e-82: 250: 30.36
+	At
		794930 PIP22_ARATH (7-245): 6.2e-84: 253: 32.02		PIP15_ARATH (10-245): 8.73e-83: 250: 33.33
+	At
		955409 PIP27_ARATH (7-245): 9.48e-83: 250: 33.33		PIP27_ARATH (9-243): 5.63e-84: 253: 34.29
+	At
		955444 PIP26_ARATH (2-245): 2.18e-82: 250: 32.95		PIP27_ARATH (9-243): 5.63e-84: 253: 34.29
+	At
		794706 PIP27_ARATH (7-245): 9.48e-83: 250: 33.33		PIP21_ARATH (10-243): 2.81e-83: 252: 31.45
+	At
		794919 PIP26_ARATH (2-245): 2.18e-82: 250: 32.95		PIP21_ARATH (10-243): 2.81e-83: 252: 31.45
+	At
		902174 PIP27_ARATH (7-245): 9.48e-83: 250: 33.33		PIP11_ARATH (10-245): 1.7e-83: 252: 30.89
+	At
		955411 PIP27_ARATH (7-245): 9.48e-83: 250: 33.33		PIP13_ARATH (10-245): 3.99e-83: 251: 31.71
+	At
		996330 PIP26_ARATH (2-245): 2.18e-82: 250: 32.95		PIP13_ARATH (10-245): 3.99e-83: 251: 31.71
+	At
		1227093 PIP26_ARATH (2-245): 2.18e-82: 250: 32.95		PIP15_ARATH (10-245): 8.73e-83: 250: 33.33
+	Hs
		670313 AQP1_HUMAN (11-244): 3.78e-83: 251: 35.44		AQP1_HUMAN (9-239): 1.38e-82: 249: 39.32
+	At
		673352 PIP27_ARATH (7-245): 9.48e-83: 250: 33.33		PIP23_ARATH (9-243): 1.81e-82: 250: 31.33
+	At
		955410 PIP27_ARATH (7-245): 9.48e-83: 250: 33.33		PIP12_ARATH (9-245): 1.03e-82: 250: 30.36
+	At
		988438 PIP26_ARATH (2-245): 2.18e-82: 250: 32.95		PIP12_ARATH (9-245): 1.03e-82: 250: 30.36