HitPredict

Interactor 1: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Interactor 2: MED15 (Q96RN5)
Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein)
Gene: MED15

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10235267
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 551 Hs			1 788
+	Hs
		323867 TF65_HUMAN (1-551): 0: 601: 100.00		SC31A_HUMAN (137-653): 5.32e-32: 136: 16.12
+	Hs
		1045222 TF65_HUMAN (1-551): 0: 601: 100.00		EP300_HUMAN (84-540): 1.67e-12: 73.7: 16.81
+	Hs
		1045858 TF65_HUMAN (1-551): 0: 601: 100.00		CHD7_HUMAN (61-442): 2.37e-12: 73.3: 8.81
+	Hs
		1045596 TF65_HUMAN (1-551): 0: 601: 100.00		CBP_HUMAN (139-603): 5.7e-09: 62.1: 11.61
+	Mm
		107065 TF65_MOUSE (1-551): 0: 577: 87.88		F8VPR5_MOUSE (139-603): 4.12e-11: 69: 11.80
+	Mm
		852340 TF65_MOUSE (1-551): 0: 577: 87.88		CBP_MOUSE (139-603): 4.08e-11: 69: 11.80
+	Hs
		323868 REL_HUMAN (12-523): 3.58e-165: 484: 41.64		SC31A_HUMAN (137-653): 5.32e-32: 136: 16.12
+	Hs
		169432 NFKB1_HUMAN (7-451): 2.24e-153: 465: 29.51		HGS_HUMAN (71-479): 5.35e-23: 107: 18.08
+	Hs
		1048836 REL_HUMAN (12-523): 3.58e-165: 484: 41.64		EP300_HUMAN (84-540): 1.67e-12: 73.7: 16.81
+	Hs
		1048945 REL_HUMAN (12-523): 3.58e-165: 484: 41.64		CBP_HUMAN (139-603): 5.7e-09: 62.1: 11.61
+	Hs
		626199 NFKB1_HUMAN (7-451): 2.24e-153: 465: 29.51		EP300_HUMAN (84-540): 1.67e-12: 73.7: 16.81
+	Hs
		1106400 NFAC2_HUMAN (4-527): 1.27e-110: 353: 18.97		CABIN_HUMAN (71-522): 4e-22: 104: 11.48
+	Mm
		1490171 NFAT5_MOUSE (6-471): 3.36e-100: 333: 17.26		NFAT5_MOUSE (73-566): 5.9e-25: 114: 17.80
+	Hs
		169365 NFAT5_HUMAN (6-470): 1.93e-99: 331: 16.67		HGS_HUMAN (71-479): 5.35e-23: 107: 18.08
+	Hs
		1067281 NFAC2_HUMAN (4-527): 1.27e-110: 353: 18.97		EP300_HUMAN (84-540): 1.67e-12: 73.7: 16.81
+	Hs
		1106362 NFAC2_HUMAN (4-527): 1.27e-110: 353: 18.97		CBP_HUMAN (139-603): 5.7e-09: 62.1: 11.61
+	Hs
		1133404 NFAC4_HUMAN (5-461): 5.81e-101: 326: 17.82		CBP_HUMAN (139-603): 5.7e-09: 62.1: 11.61
+	Hs
		340877 NFAC1_HUMAN (1-503): 2.81e-93: 307: 18.89		EP300_HUMAN (84-540): 1.67e-12: 73.7: 16.81
+	Hs
		340920 NFAC1_HUMAN (1-503): 2.81e-93: 307: 18.89		CBP_HUMAN (139-603): 5.7e-09: 62.1: 11.61
+	Mm
		1455913 PCLO_MOUSE (276-519): 7.41e-11: 67.6: 10.48		PCLO_MOUSE (48-639): 1.52e-13: 77.1: 12.31