HitPredict

Interactor 1: BACD2 (Q13829)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial)
Gene: TNFAIP1

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 316 Hs			1 2725
+	Hs
		1052911 BACD1_HUMAN (13-316): 1.46e-119: 348: 65.13		FLNC_HUMAN (1-2725): 0: 2507: 100.00
+	Hs
		1052954 KCND2_HUMAN (7-230): 2.3e-70: 231: 15.42		FLNC_HUMAN (1-2725): 0: 2507: 100.00
+	Hs
		598316 BACD3_HUMAN (1-311): 7.45e-121: 351: 70.70		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		598252 BACD1_HUMAN (13-316): 1.46e-119: 348: 65.13		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		598355 KCND2_HUMAN (7-230): 2.3e-70: 231: 15.42		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		598194 KCTD9_HUMAN (3-176): 1.68e-42: 152: 24.60		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		598229 KCD17_HUMAN (28-180): 4.05e-42: 149: 26.42		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		261290 KCTD9_HUMAN (3-176): 1.68e-42: 152: 24.60		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Dm
		1364784 Q9W579_DROME (16-203): 2.91e-42: 146: 21.47		FLNA_DROME (758-2724): 0: 1012: 33.19
+	Hs
		608218 KCNA4_HUMAN (3-229): 7.08e-49: 174: 15.55		ACTN2_HUMAN (2-387): 2.32e-122: 412: 26.00
+	Rn
		580274 KCNA5_RAT (2-230): 8.41e-41: 151: 12.55		ACTN1_RAT (13-382): 7.06e-123: 414: 26.30
+	Hs
		211604 KCTD9_HUMAN (3-176): 1.68e-42: 152: 24.60		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		521580 KCTD6_HUMAN (30-168): 3.88e-35: 129: 35.71		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		70404 KCTD6_HUMAN (30-168): 3.88e-35: 129: 35.71		B2R8Y4_HUMAN (23-388): 3.96e-120: 406: 27.63
+	Hs
		993276 KCTD6_HUMAN (30-168): 3.88e-35: 129: 35.71		ACTN3_HUMAN (23-388): 4.53e-120: 406: 27.63
+	Ce
		1095233 Q9TZA6_CAEEL (24-202): 9.22e-48: 161: 30.22		Q23158_CAEEL (16-315): 1.14e-104: 361: 28.93
+	Hs
		963357 KCTD9_HUMAN (3-176): 1.68e-42: 152: 24.60		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Ce
		954549 P91563_CAEEL (27-194): 6.02e-43: 149: 27.98		Q23158_CAEEL (16-315): 1.14e-104: 361: 28.93