Interactor 1: KEAP1 (Q14145)
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19)
Gene: KEAP1

Interactor 2: NF2L1 (Q14494)
Endoplasmic reticulum membrane sensor NFE2L1 (Locus control region-factor 1) (LCR-F1) (Nuclear factor erythroid 2-related factor 1) (NF-E2-related factor 1) (NFE2-related factor 1) (Nuclear factor, erythroid derived 2, like 1) (Protein NRF1, p120 form) (Transcription factor 11) (TCF-11) [Cleaved into: Transcription factor NRF1 (Protein NRF1, p110 form)]
Gene: NFE2L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.741

The method score is based on:

Property Details
Experiments 16687406, 29255090, 30126895, 35044719, 36163178, 21262351, 21988832
Identification Methods affinity chromatography technology, unspecified method, two hybrid, fluorescence polarization spectroscopy, phage display
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 624
Hs

1 772
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024