HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: ITPR3 (Q14573)
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 (IP3 receptor isoform 3) (IP3R-3) (InsP3R3) (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor)
Gene: ITPR3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 2671
+	Hs
		248704 PEPL_HUMAN (13-748): 2.34e-35: 147: 12.35		ITPR3_HUMAN (1-2671): 0: 4288: 100.00
+	Hs
		772802 MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76		ITPR3_HUMAN (1-2671): 0: 4288: 100.00
+	Hs
		157373 CTRO_HUMAN (122-718): 9.4e-15: 81: 9.87		ITPR3_HUMAN (1-2671): 0: 4288: 100.00
+	Hs
		1052016 CALD1_HUMAN (1-793): 4.89e-41: 163: 100.00		ITPR1_HUMAN (2-2663): 0: 3900: 60.67
+	Hs
		1052014 CALD1_HUMAN (1-793): 4.89e-41: 163: 100.00		ITPR2_HUMAN (3-2663): 0: 3897: 64.52
+	Hs
		248703 PEPL_HUMAN (13-748): 2.34e-35: 147: 12.35		ITPR2_HUMAN (3-2663): 0: 3897: 64.52
+	Hs
		1128998 PLEC_HUMAN (12-768): 3.36e-22: 105: 12.58		ITPR1_HUMAN (2-2663): 0: 3900: 60.67
+	Hs
		772801 MYH9_HUMAN (10-659): 9.61e-22: 103: 9.76		ITPR2_HUMAN (3-2663): 0: 3897: 64.52
+	Hs
		587557 DESP_HUMAN (13-640): 3.04e-22: 105: 14.35		RYR1_HUMAN (1714-2183): 9.66e-50: 199: 19.89
+	Hs
		587673 DESP_HUMAN (13-640): 3.04e-22: 105: 14.35		RYR3_HUMAN (1710-1960): 2.87e-45: 184: 24.06
+	Mm
		97963 MYH1_MOUSE (4-608): 8.03e-20: 97.5: 11.26		RYR2_MOUSE (1712-2183): 2.45e-45: 184: 19.37
+	Mm
		97989 PLEC_MOUSE (1-552): 3.05e-09: 63.2: 13.37		RYR2_MOUSE (1712-2183): 2.45e-45: 184: 19.37