Interactor 1: RPN7 (Q06103)
26S proteasome regulatory subunit RPN7
Gene: RPN7

Interactor 2: RPN6 (Q12377)
26S proteasome regulatory subunit RPN6 (Proteasome non-ATPase subunit 4)
Gene: RPN6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 11805826, 16429126, 19446323, 23911091, 24412063, 9741626, 10873636, 16554755, 37968396, 31848235, 14759368
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, PCI~RPN7, PCI~RPN7_PSMD6_C, RPN6_C_helix~RPN7_PSMD6_C
Common GO terms GO:0000502 - proteasome complex
GO:0005198 - structural molecule activity
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 429
Sc

1 434
+ Hs
+ Dm
+ Mm
+ Hs
+ At
+ Hs
+ Hs
+ Sp
+ At
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Zm
+ At
+ Mm
+ Dm

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Last updated: 11Aug2025