HitPredict

Interactor 1: TNR9 (Q07011)
Tumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137)
Gene: TNFRSF9

Interactor 2: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 913
+	Hs
		163288 TR10B_HUMAN (31-119): 1.92e-17: 82.9: 21.28		DDR1_HUMAN (1-913): 0: 911: 100.00
+	Hs
		1063003 TR19L_HUMAN (30-125): 1.6e-13: 71.4: 24.27		DDR1_HUMAN (1-913): 0: 911: 100.00
+	Hs
		557479 CELR2_HUMAN (14-138): 9.01e-32: 125: 25.37		SRC_HUMAN (361-912): 1.25e-129: 402: 23.42
+	Hs
		557105 TNR6_HUMAN (4-134): 4.29e-22: 94.8: 20.28		SRC_HUMAN (361-912): 1.25e-129: 402: 23.42
+	Hs
		541374 TNR3_HUMAN (24-172): 1.01e-35: 133: 28.24		FGFR1_HUMAN (540-905): 4.74e-109: 357: 32.52
+	Mm
		669442 TNR1B_MOUSE (22-180): 1.32e-34: 131: 26.92		NTRK1_MOUSE (604-906): 6.87e-105: 345: 43.23
+	Hs
		557078 TNR1A_HUMAN (27-139): 6.71e-09: 57.9: 20.90		SRC_HUMAN (361-912): 1.25e-129: 402: 23.42
+	Hs
		127635 TR10A_HUMAN (31-119): 1.12e-20: 92.2: 24.47		FGFR3_HUMAN (551-905): 4.72e-112: 364: 31.35
+	Hs
		127634 TR10A_HUMAN (31-119): 1.12e-20: 92.2: 24.47		FGFR4_HUMAN (554-910): 1.49e-107: 352: 33.87
+	Hs
		163227 TR10B_HUMAN (31-119): 1.92e-17: 82.9: 21.28		FGFR1_HUMAN (540-905): 4.74e-109: 357: 32.52
+	Hs
		462989 TNR6_HUMAN (4-134): 4.29e-22: 94.8: 20.28		YES_HUMAN (563-907): 1.74e-105: 339: 31.59
+	Rn
		450769 TNR16_RAT (19-91): 8.12e-10: 60.6: 26.92		NTRK2_RAT (604-906): 6.77e-105: 345: 43.89
+	Hs
		466579 TNR16_HUMAN (19-91): 1.26e-09: 59.8: 28.21		NTRK2_HUMAN (604-906): 1.7e-104: 345: 43.89
+	Rn
		450765 TNR16_RAT (19-91): 8.12e-10: 60.6: 26.92		NTRK1_RAT (604-906): 3.57e-104: 343: 42.90
+	Hs
		411208 TNR16_HUMAN (19-91): 1.26e-09: 59.8: 28.21		NTRK1_HUMAN (607-902): 1.44e-66: 240: 45.27
+	Rn
		450767 TNR16_RAT (19-91): 8.12e-10: 60.6: 26.92		NTRK3_RAT (607-905): 1.69e-63: 232: 40.41