HitPredict

Interactor 1: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk

Interactor 2: Q9W3N8 (Q9W3N8)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: Nek2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 735
+	Hs
		987773 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		MINK1_HUMAN (13-717): 9.41e-132: 424: 20.39
+	Hs
		463831 LYN_HUMAN (3-199): 4e-35: 131: 25.24		TNIK_HUMAN (1-711): 8.56e-139: 443: 20.89
+	Hs
		463607 LYN_HUMAN (3-199): 4e-35: 131: 25.24		MARK2_HUMAN (1-667): 1.65e-138: 428: 19.97
+	Hs
		463648 LYN_HUMAN (3-199): 4e-35: 131: 25.24		MINK1_HUMAN (13-717): 9.41e-132: 424: 20.39
+	Hs
		440132 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		MARK2_HUMAN (1-667): 1.65e-138: 428: 19.97
+	Hs
		463345 LYN_HUMAN (3-199): 4e-35: 131: 25.24		MARK3_HUMAN (5-667): 1.74e-135: 419: 18.46
+	Hs
		440144 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		MINK1_HUMAN (13-717): 9.41e-132: 424: 20.39
+	Hs
		439960 LCK_HUMAN (3-200): 4.18e-32: 123: 26.54		MARK3_HUMAN (5-667): 1.74e-135: 419: 18.46
+	Hs
		594130 NCK1_HUMAN (5-143): 2.42e-20: 89.4: 32.35		TNIK_HUMAN (1-711): 8.56e-139: 443: 20.89
+	Hs
		463709 LYN_HUMAN (3-199): 4e-35: 131: 25.24		MARK4_HUMAN (5-638): 3.38e-128: 400: 16.82
+	Hs
		463506 LYN_HUMAN (3-199): 4e-35: 131: 25.24		ROCK1_HUMAN (17-512): 1.85e-120: 393: 23.11
+	Hs
		594048 NCK1_HUMAN (5-143): 2.42e-20: 89.4: 32.35		MINK1_HUMAN (13-717): 9.41e-132: 424: 20.39
+	Hs
		463366 LYN_HUMAN (3-199): 4e-35: 131: 25.24		AKT2_HUMAN (2-341): 6.55e-125: 382: 25.14
+	Mm
		431326 SRC_MOUSE (4-208): 1.13e-32: 125: 26.09		AKT1_MOUSE (2-349): 8.39e-127: 387: 24.44
+	Hs
		557128 SRC_HUMAN (4-208): 1.27e-32: 124: 25.65		AKT1_HUMAN (2-349): 7.46e-127: 387: 24.44
+	Hs
		593917 NCK1_HUMAN (5-143): 2.42e-20: 89.4: 32.35		MARK3_HUMAN (5-667): 1.74e-135: 419: 18.46
+	Hs
		728082 CSK_HUMAN (2-136): 3.19e-25: 103: 36.30		AKT1_HUMAN (2-349): 7.46e-127: 387: 24.44
+	Hs
		987741 GRB2_HUMAN (1-210): 1.15e-62: 195: 62.62		NEK8_HUMAN (16-288): 4.6e-41: 162: 34.67
+	Hs
		362313 ABL1_HUMAN (4-138): 2.71e-23: 99: 36.43		NEK8_HUMAN (16-288): 4.6e-41: 162: 34.67
+	Hs
		594036 NCK1_HUMAN (5-143): 2.42e-20: 89.4: 32.35		NEK8_HUMAN (16-288): 4.6e-41: 162: 34.67