HitPredict

Interactor 1: DMWD (Q09019)
Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9)
Gene: DMWD

Interactor 2: WDFY3 (Q8IZQ1)
WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)
Gene: WDFY3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0043204 - perikaryon
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 674 Hs			1 3526
+	Hs
		992893 RACK1_HUMAN (160-449): 3.14e-50: 179: 13.61		FAN_HUMAN (2475-3286): 3.93e-177: 573: 25.38
+	Sp
		148819 TAF73_SCHPO (214-446): 5.67e-57: 206: 18.70		TAF5_SCHPO (3161-3476): 5.94e-20: 99.6: 11.78
+	Hs
		261352 TBL1X_HUMAN (321-629): 2.73e-33: 137: 12.73		TBL1X_HUMAN (3122-3438): 1.5e-35: 147: 14.67
+	Hs
		261437 TBL1Y_HUMAN (321-638): 1.19e-33: 137: 12.09		TBL1X_HUMAN (3122-3438): 1.5e-35: 147: 14.67
+	Hs
		1410246 TBL1Y_HUMAN (321-638): 1.19e-33: 137: 12.09		TBL1R_HUMAN (3122-3438): 7.51e-34: 141: 14.16
+	Hs
		261440 TBL1X_HUMAN (321-629): 2.73e-33: 137: 12.73		TBL1R_HUMAN (3122-3438): 7.51e-34: 141: 14.16
+	Hs
		965276 NLE1_HUMAN (61-398): 7.32e-56: 199: 12.69		WDR5_HUMAN (2882-3106): 8.48e-14: 77.7: 8.88
+	Hs
		845264 LIS1_HUMAN (22-356): 3.06e-55: 195: 13.24		WDR5_HUMAN (2882-3106): 8.48e-14: 77.7: 8.88
+	Hs
		1403337 TBL1R_HUMAN (321-629): 2.95e-33: 136: 12.46		RUFY1_HUMAN (3273-3521): 1.94e-30: 133: 23.26
+	Hs
		964829 RACK1_HUMAN (160-449): 3.14e-50: 179: 13.61		WDR5_HUMAN (2882-3106): 8.48e-14: 77.7: 8.88
+	Hs
		965071 WDR5B_HUMAN (43-353): 4.4e-50: 179: 9.64		WDR5_HUMAN (2882-3106): 8.48e-14: 77.7: 8.88
+	Hs
		1360175 FBXW7_HUMAN (89-349): 1.06e-27: 121: 7.44		RUFY2_HUMAN (3427-3523): 2.23e-27: 123: 31.96
+	Hs
		222461 WDR5_HUMAN (402-629): 1.89e-17: 86: 8.12		PLRG1_HUMAN (2934-3299): 2.17e-38: 155: 13.66
+	Dm
		1463899 WDS_DROME (357-633): 3.7e-27: 115: 11.23		WDS_DROME (2931-3154): 1.51e-26: 116: 13.97
+	Hs
		965141 FBXW7_HUMAN (89-349): 1.06e-27: 121: 7.44		WDR5_HUMAN (2882-3106): 8.48e-14: 77.7: 8.88
+	Hs
		209230 PRP4_HUMAN (366-643): 6.79e-24: 107: 11.11		WDR5_HUMAN (2882-3106): 8.48e-14: 77.7: 8.88
+	Hs
		964797 WDR5_HUMAN (402-629): 1.89e-17: 86: 8.12		WDR5_HUMAN (2882-3106): 8.48e-14: 77.7: 8.88