Protein: FAN
Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation)

Gene: FAN, NSMAF
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q92636

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006672 - ceramide metabolic process
GO:0007165 - signal transduction
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

952999

ACTB
Actin, cytoplasmic 1

1

7

Small-scale

0.757

High

992893

RACK1
Small ribosomal subunit protein RACK1

1

15

Small-scale

0.740

High

610806

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.691

High

821486

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.691

High

876096

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.691

High

882069

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.691

High

899162

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.691

High

899506

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.691

High

1007178

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.691

High

1366341

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.691

High

1366344

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

3

18

High-throughput

0.686

High

622650

TNR1A
Tumor necrosis factor receptor superfamily member 1A

3

5

Small-scale

0.661

High

325018

HEXI1
Protein HEXIM1

3

0

High-throughput

0.638

High

1059053

TRHY
Trichohyalin

2

18

High-throughput

0.628

High

870492

PPCE
Prolyl endopeptidase

2

0

High-throughput

0.602

High

1098654

SBP1
Methanethiol oxidase

2

0

High-throughput

0.602

High

1366343

MLP3B
Microtubule-associated protein 1 light chain 3 beta

2

18

High-throughput

0.595

High

1366340

FAN
Protein FAN

1

11

High-throughput

0.575

High

326755

DUS14
Dual specificity protein phosphatase 14

2

1

High-throughput

0.574

High

1236028

HPHL1
Ferroxidase HEPHL1

2

1

High-throughput

0.574

High

1286449

DSG4
Desmoglein-4

2

2

High-throughput

0.574

High

1316178

DCP1B
mRNA-decapping enzyme 1B

1

6

Small-scale

0.552

High

1366346

DCP1A
mRNA-decapping enzyme 1A

1

4

Small-scale

0.552

High

328095

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

18

High-throughput

0.550

High

217498

E41L2
Band 4.1-like protein 2

1

5

High-throughput

0.536

High

577838

PLAK
Junction plakoglobin

1

8

High-throughput

0.536

High

909119

NEK4
Serine/threonine-protein kinase Nek4

1

10

High-throughput

0.536

High

1243758

FXL19
F-box/LRR-repeat protein 19

1

3

High-throughput

0.536

High

1338504

DOCK8
Dedicator of cytokinesis protein 8

1

2

High-throughput

0.536

High

1350546

NEK9
Serine/threonine-protein kinase Nek9

1

6

High-throughput

0.536

High

1366345

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

18

High-throughput

0.536

High

1366347

PFD2
Prefoldin subunit 2

1

2

High-throughput

0.536

High

1366349

PKP3
Plakophilin-3

1

11

High-throughput

0.536

High

896597

VASP
Vasodilator-stimulated phosphoprotein

1

0

Small-scale

0.530

High

1358811

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.513

High

1366348

PADI3
Protein-arginine deiminase type-3

1

0

High-throughput

0.513

High

952277

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

18

High-throughput

0.501

High

1366342

MLP3C
Microtubule-associated protein 1 light chain 3 gamma

1

18

High-throughput

0.501

High

618155

K2C4
Keratin, type II cytoskeletal 4

1

5

High-throughput

0.445

High

1352421

SH3R2
E3 ubiquitin-protein ligase SH3RF2

1

2

Small-scale

0.437

High

1207481

CAHM4
Calcium homeostasis modulator protein 4

2

0

High-throughput

0.328

High

1286399

LYG2
Lysozyme g-like protein 2

2

0

High-throughput

0.328

High

62777

XIRP2
Xin actin-binding repeat-containing protein 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025