HitPredict

Interactor 1: F8WI37 (F8WI37)
Histone-lysine N-methyltransferase 2C (EC 2.1.1.364)
Gene: Kmt2c

Interactor 2: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	23892456
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4904 Mm			1 305
+	Mm
		1283117 KMT2C_MOUSE (1-4904): 0: 2995: 99.98		NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00
+	Hs
		662249 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		PAX7_HUMAN (80-304): 1.42e-34: 133: 15.06
+	Hs
		725285 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		TLX1_HUMAN (29-215): 7.18e-34: 128: 22.80
+	Hs
		685267 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		PAX6_HUMAN (46-285): 2.02e-31: 123: 14.82
+	Hs
		226574 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		TLX2_HUMAN (60-158): 7.64e-27: 108: 30.39
+	Hs
		225064 KMT2C_HUMAN (1-4904): 0: 2819: 84.61		TLX3_HUMAN (89-153): 9.36e-09: 57.4: 43.08
+	Mm
		1204123 EHMT1_MOUSE (4430-4900): 1.15e-86: 316: 17.22		NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00
+	Mm
		1283232 EHMT2_MOUSE (4443-4900): 4.53e-83: 304: 17.43		NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00
+	Mm
		1222435 EZH2_MOUSE (4557-4886): 8.53e-81: 287: 21.49		NANOG_MOUSE (1-305): 1.88e-60: 196: 100.00
+	Hs
		725321 EHMT1_HUMAN (4430-4900): 3.18e-85: 311: 16.83		TLX1_HUMAN (29-215): 7.18e-34: 128: 22.80
+	Hs
		685351 EHMT1_HUMAN (4430-4900): 3.18e-85: 311: 16.83		PAX6_HUMAN (46-285): 2.02e-31: 123: 14.82
+	Hs
		725305 EHMT2_HUMAN (4430-4900): 5.37e-81: 297: 16.73		TLX1_HUMAN (29-215): 7.18e-34: 128: 22.80
+	Hs
		685313 EHMT2_HUMAN (4430-4900): 5.37e-81: 297: 16.73		PAX6_HUMAN (46-285): 2.02e-31: 123: 14.82
+	Hs
		226601 EHMT1_HUMAN (4430-4900): 3.18e-85: 311: 16.83		TLX2_HUMAN (60-158): 7.64e-27: 108: 30.39
+	Hs
		685178 CHD3_HUMAN (319-655): 1.82e-77: 290: 17.41		PAX6_HUMAN (46-285): 2.02e-31: 123: 14.82
+	Hs
		226586 EHMT2_HUMAN (4430-4900): 5.37e-81: 297: 16.73		TLX2_HUMAN (60-158): 7.64e-27: 108: 30.39
+	Hs
		851767 CHD4_HUMAN (328-674): 1.1e-72: 275: 14.95		NKX21_HUMAN (51-158): 8.48e-29: 115: 33.33
+	Hs
		225114 EHMT1_HUMAN (4430-4900): 3.18e-85: 311: 16.83		TLX3_HUMAN (89-153): 9.36e-09: 57.4: 43.08
+	Hs
		1088425 CHD3_HUMAN (319-655): 1.82e-77: 290: 17.41		ZFHX4_HUMAN (97-181): 9.04e-12: 67.7: 27.06
+	Hs
		225080 EHMT2_HUMAN (4430-4900): 5.37e-81: 297: 16.73		TLX3_HUMAN (89-153): 9.36e-09: 57.4: 43.08