Interactor 1: G1SZM2 (G1SZM2)
Amyloid-beta A4 protein
Gene: APP
Interactor 2: SORL (Q95209)
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)
Gene: SORL1
Species: Oryctolagus cuniculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.681 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17761669 |
| Identification Methods | unspecified method, affinity chromatography technology |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | APP_Cu_bd~fn3, APP_N~fn3 |
| Common GO terms | GO:0005615 - extracellular space GO:0005783 - endoplasmic reticulum GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0006897 - endocytosis and 1 others more... |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
