HitPredict

Interactor 1: VPS2B (Q0WTY4)
Vacuolar protein sorting-associated protein 2 homolog 2 (AtVPS2-2) (Charged multivesicular body protein 2 homolog 2) (ESCRT-III complex subunit VPS2 homolog 2)
Gene: VPS2.2

Interactor 2: VPS2B (Q0WTY4)
Vacuolar protein sorting-associated protein 2 homolog 2 (AtVPS2-2) (Charged multivesicular body protein 2 homolog 2) (ESCRT-III complex subunit VPS2 homolog 2)
Gene: VPS2.2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.752

Property	Details
Experiments	22010978
Identification Methods	affinity chromatography technology, two hybrid, protein complementation assay, bimolecular fluorescence complementation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0000815 - ESCRT III complex GO:0007034 - vacuolar transport GO:0015031 - protein transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 222 At			1 222
+	At
		1082317 VPS2A_ARATH (2-222): 1.91e-54: 175: 40.99		VPS2B_ARATH (1-222): 1.53e-50: 165: 100.00
+	Sc
		781314 DID4_YEAST (3-221): 5.08e-48: 159: 33.04		DID4_YEAST (3-221): 5.08e-48: 159: 33.04
+	At
		1424668 VPS2A_ARATH (2-222): 1.91e-54: 175: 40.99		VP241_ARATH (1-220): 1.44e-41: 142: 28.13
+	At
		1082300 VPS2B_ARATH (1-222): 1.53e-50: 165: 100.00		CHM1A_ARATH (12-220): 2.56e-43: 146: 22.49
+	Dm
		1482281 Q9VN02_DROME (1-220): 1.93e-46: 154: 24.32		Q9VRJ5_DROME (2-206): 3.46e-45: 151: 31.71
+	Hs
		221818 CHM2A_HUMAN (3-221): 2.71e-45: 151: 35.62		CHM2A_HUMAN (3-221): 2.71e-45: 151: 35.62
+	Hs
		221896 CHM2A_HUMAN (3-221): 2.71e-45: 151: 35.62		CHMP3_HUMAN (1-220): 2.54e-44: 149: 21.62
+	At
		1082319 VPS2B_ARATH (1-222): 1.53e-50: 165: 100.00		CHM1B_ARATH (12-220): 6.17e-39: 134: 22.49
+	Dm
		1469210 Q9VN02_DROME (1-220): 1.93e-46: 154: 24.32		Q9VBI3_DROME (3-199): 1.9e-41: 142: 36.04
+	Sc
		781005 DID4_YEAST (3-221): 5.08e-48: 159: 33.04		VPS24_YEAST (7-221): 6.2e-38: 132: 17.59
+	Dm
		1377975 Q9VN02_DROME (1-220): 1.93e-46: 154: 24.32		Q95SH2_DROME (14-221): 2.95e-38: 133: 25.48
+	Dm
		1377977 Q9VRJ5_DROME (2-206): 3.46e-45: 151: 31.71		Q95SH2_DROME (14-221): 2.95e-38: 133: 25.48
+	Hs
		221885 CHM2A_HUMAN (3-221): 2.71e-45: 151: 35.62		CHM1A_HUMAN (14-221): 3.16e-36: 127: 20.67
+	Hs
		221862 CHM2A_HUMAN (3-221): 2.71e-45: 151: 35.62		CHM1B_HUMAN (14-220): 2.41e-34: 122: 24.16
+	Sc
		781332 DID4_YEAST (3-221): 5.08e-48: 159: 33.04		DID2_YEAST (14-220): 6.37e-30: 111: 17.39
+	Ce
		1166323 Q9U2F6_CAEEL (3-221): 4.04e-50: 164: 31.33		Q18886_CAEEL (1-214): 5.64e-14: 70.2: 14.41
+	Dm
		1345400 Q9VN02_DROME (1-220): 1.93e-46: 154: 24.32		CHM4_DROME (3-216): 1.37e-14: 71.7: 16.06
+	Hs
		221882 CHM2A_HUMAN (3-221): 2.71e-45: 151: 35.62		CHM4B_HUMAN (8-206): 6.83e-15: 72.5: 19.32
+	Dm
		1345401 Q9VRJ5_DROME (2-206): 3.46e-45: 151: 31.71		CHM4_DROME (3-216): 1.37e-14: 71.7: 16.06