HitPredict - High confidence protein-protein interactions

Interactor 1: CHM2A (O43633)
Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1)
Gene: CHMP2A

Interactor 2: CHM1B (Q7LBR1)
Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)
Gene: CHMP1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0000421 - autophagosome membrane GO:0000776 - kinetochore GO:0000815 - ESCRT III complex GO:0001778 - plasma membrane repair GO:0005643 - nuclear pore and 33 others more... GO:0005765 - lysosomal membrane GO:0005771 - multivesicular body GO:0005828 - kinetochore microtubule GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006914 - autophagy GO:0006997 - nucleus organization GO:0007080 - mitotic metaphase chromosome alignment GO:0010824 - regulation of centrosome duplication GO:0015031 - protein transport GO:0019904 - protein domain specific binding GO:0030117 - membrane coat GO:0030496 - midbody GO:0031468 - nuclear membrane reassembly GO:0032509 - endosome transport via multivesicular body sorting pathway GO:0032585 - multivesicular body membrane GO:0036258 - multivesicular body assembly GO:0039702 - viral budding via host ESCRT complex GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0045184 - establishment of protein localization GO:0045324 - late endosome to vacuole transport GO:0046761 - viral budding from plasma membrane GO:0051469 - vesicle fusion with vacuole GO:0061763 - multivesicular body-lysosome fusion GO:0061952 - midbody abscission GO:0070062 - extracellular exosome GO:0071985 - multivesicular body sorting pathway GO:0090148 - membrane fission GO:0097352 - autophagosome maturation GO:1901673 - regulation of mitotic spindle assembly GO:1902774 - late endosome to lysosome transport GO:1904903 - ESCRT III complex disassembly GO:1904930 - amphisome membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1	222
Hs

1	199

Service provided by Combinatics, Japan

Last updated: 11Aug2025