HitPredict

Interactor 1: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Interactor 2: M3K20 (Q9NYL2)
Mitogen-activated protein kinase kinase kinase 20 (EC 2.7.11.25) (Human cervical cancer suppressor gene 4 protein) (HCCS-4) (Leucine zipper- and sterile alpha motif-containing kinase) (MLK-like mitogen-activated protein triple kinase) (Mitogen-activated protein kinase kinase kinase MLT) (Mixed lineage kinase 7) (Mixed lineage kinase-related kinase) (MLK-related kinase) (MRK) (Sterile alpha motif- and leucine zipper-containing kinase AZK)
Gene: MAP3K20

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 378 Hs			1 800
+	Hs
		972460 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		M3K10_HUMAN (10-326): 2.28e-116: 376: 38.66
+	Hs
		1082784 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		M3K11_HUMAN (12-331): 1.29e-112: 364: 37.01
+	Hs
		1082818 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		M3K21_HUMAN (9-326): 1.09e-109: 360: 36.70
+	Hs
		789071 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		ABL2_HUMAN (9-338): 3.12e-105: 351: 30.50
+	Hs
		433368 CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00		YES_HUMAN (2-268): 9.65e-100: 321: 29.86