HitPredict

Interactor 1: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Interactor 2: MYH2 (Q9UKX2)
Myosin-2 (Myosin heavy chain 2) (Myosin heavy chain 2a) (MyHC-2a) (Myosin heavy chain IIa) (MyHC-IIa) (Myosin heavy chain, skeletal muscle, adult 2)
Gene: MYH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 826 Hs			1 1941
+	Hs
		522551 HIF1A_HUMAN (1-826): 0: 741: 100.00		MYH1_HUMAN (1-1941): 0: 1115: 94.54
+	Hs
		1085739 HIF1A_HUMAN (1-826): 0: 741: 100.00		MYH4_HUMAN (1-1941): 0: 1113: 91.40
+	Hs
		528376 HIF1A_HUMAN (1-826): 0: 741: 100.00		MYH6_HUMAN (3-1933): 0: 1090: 80.22
+	Hs
		649049 ARNT_HUMAN (7-652): 5.14e-103: 338: 17.06		MYH9_HUMAN (28-1932): 0: 929: 39.90
+	Hs
		725093 NCOA3_HUMAN (1-746): 4.42e-98: 335: 15.31		MYH9_HUMAN (28-1932): 0: 929: 39.90
+	Hs
		502916 HIF1A_HUMAN (1-826): 0: 741: 100.00		MYH3_HUMAN (732-1213): 4.32e-15: 84: 13.31
+	Hs
		649050 ARNT_HUMAN (7-652): 5.14e-103: 338: 17.06		MYH10_HUMAN (987-1941): 1.59e-60: 233: 18.69
+	Dm
		1096484 SIMA_DROME (4-722): 1.28e-95: 329: 25.42		MYSN_DROME (1127-1939): 9.22e-48: 191: 17.58