HitPredict

Interactor 1: H31T (Q16695)
Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Gene: H3-4

Interactor 2: KDM2A (Q9Y2K7)
Lysine-specific demethylase 2A (EC 1.14.11.27) (CXXC-type zinc finger protein 8) (F-box and leucine-rich repeat protein 11) (F-box protein FBL7) (F-box protein Lilina) (F-box/LRR-repeat protein 11) (JmjC domain-containing histone demethylation protein 1A) ([Histone-H3]-lysine-36 demethylase 1A)
Gene: KDM2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	16362057
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 1162
+	Hs
		935393 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		KDM2A_HUMAN (1-1162): 0: 1354: 100.00
+	Hs
		952712 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		KDM2A_HUMAN (1-1162): 0: 1354: 100.00
+	Hs
		1174697 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		KDM2A_HUMAN (1-1162): 0: 1354: 100.00
+	Hs
		935008 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		952482 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		1174601 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		KDM2B_HUMAN (15-1162): 0: 1040: 37.75
+	Hs
		256400 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		PHF2_HUMAN (4-441): 4.67e-168: 528: 29.19
+	Hs
		256412 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		PHF2_HUMAN (4-441): 4.67e-168: 528: 29.19
+	Hs
		256401 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		PHF2_HUMAN (4-441): 4.67e-168: 528: 29.19
+	Hs
		256416 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		PHF2_HUMAN (4-441): 4.67e-168: 528: 29.19
+	Ce
		445734 H3_CAEEL (1-136): 2.7e-60: 183: 94.85		KDM7_CAEEL (3-432): 9.04e-169: 524: 26.21
+	Hs
		935373 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		1086352 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		952701 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		PHF8_HUMAN (12-406): 1.45e-164: 517: 37.69
+	Hs
		934681 H31_HUMAN (1-136): 6.88e-62: 187: 97.06		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		975268 H31T_HUMAN (1-136): 2.65e-61: 186: 100.00		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		952284 H33_HUMAN (1-136): 4.53e-61: 185: 93.38		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Hs
		975278 H32_HUMAN (1-136): 1.34e-60: 184: 96.32		KMT2A_HUMAN (360-609): 1.68e-47: 188: 20.73
+	Mm
		139069 H33_MOUSE (1-136): 4.53e-61: 185: 93.38		KMT2B_MOUSE (372-609): 1.26e-45: 182: 20.50
+	Dm
		356110 H3_DROME (1-136): 1.34e-60: 184: 96.32		JHD1_DROME (431-568): 5.89e-28: 124: 27.54