Interactor 1: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Interactor 2: TOPB1 (Q92547)
DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-beta-binding protein 1) (TopBP1) (DNA topoisomerase II-binding protein 1)
Gene: TOPBP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 34100862, 33503405
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1488
Hs

1 1522
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Service provided by Combinatics, Japan

Last updated: 11Aug2025