Interactor 1: TAXB1 (Q3UKC1)
Tax1-binding protein 1 homolog
Gene: Tax1bp1

Interactor 2: ITCH (Q8C863)
E3 ubiquitin-protein ligase Itchy (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase Itchy homolog)
Gene: ITCH

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 27736772, 21765415, 18246070
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006915 - apoptotic process
GO:0031410 - cytoplasmic vesicle
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
GO:0039532 - negative regulation of cytoplasmic pattern recognition receptor signaling pathway
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 814
Mm

1 864
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024