HitPredict

Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Interactor 2: FEM1A (Q9BSK4)
Protein fem-1 homolog A (FEM1a) (FEM1-alpha) (Prostaglandin E receptor 4-associated protein)
Gene: FEM1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 33961781, 21145461
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Cullin
Common GO terms GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0031462 - Cul2-RING ubiquitin ligase complex
GO:0140627 - ubiquitin-dependent protein catabolic process via the C-end degron rule pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 745
Hs

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Last updated: 11Aug2025