HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: WDR25 (Q64LD2)
WD repeat-containing protein 25
Gene: WDR25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37788672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 544
+	Hs
		964927 CUL3_HUMAN (1-768): 0: 943: 100.00		WDR5_HUMAN (96-410): 2.19e-56: 194: 15.04
+	Hs
		1113779 CUL3_HUMAN (1-768): 0: 943: 100.00		POC1B_HUMAN (108-347): 2.45e-30: 125: 16.00
+	Hs
		1114438 CUL3_HUMAN (1-768): 0: 943: 100.00		NLE1_HUMAN (99-276): 2.51e-18: 89.7: 13.33
+	Hs
		1114647 CUL3_HUMAN (1-768): 0: 943: 100.00		PRP19_HUMAN (237-455): 3.53e-09: 61.2: 24.78
+	Hs
		845297 CUL4A_HUMAN (10-768): 0: 801: 38.32		LIS1_HUMAN (100-413): 2.3e-57: 198: 14.54
+	Hs
		964928 CUL4A_HUMAN (10-768): 0: 801: 38.32		WDR5_HUMAN (96-410): 2.19e-56: 194: 15.04
+	Hs
		845298 CUL4B_HUMAN (5-768): 0: 796: 36.77		LIS1_HUMAN (100-413): 2.3e-57: 198: 14.54
+	Hs
		964929 CUL4B_HUMAN (5-768): 0: 796: 36.77		WDR5_HUMAN (96-410): 2.19e-56: 194: 15.04
+	Hs
		1115406 CUL4B_HUMAN (5-768): 0: 796: 36.77		TBL1R_HUMAN (17-365): 2.96e-47: 174: 15.49
+	Hs
		1114921 CUL4A_HUMAN (10-768): 0: 801: 38.32		WDR5B_HUMAN (115-361): 4.5e-33: 130: 14.90
+	Hs
		1114950 CUL4A_HUMAN (10-768): 0: 801: 38.32		POC1B_HUMAN (108-347): 2.45e-30: 125: 16.00
+	Hs
		1115283 CUL4B_HUMAN (5-768): 0: 796: 36.77		WDR5B_HUMAN (115-361): 4.5e-33: 130: 14.90
+	Hs
		1114994 CUL4A_HUMAN (10-768): 0: 801: 38.32		SNR40_HUMAN (421-543): 2.01e-29: 120: 17.89
+	Hs
		1115313 CUL4B_HUMAN (5-768): 0: 796: 36.77		POC1B_HUMAN (108-347): 2.45e-30: 125: 16.00
+	Hs
		1115353 CUL4B_HUMAN (5-768): 0: 796: 36.77		SNR40_HUMAN (421-543): 2.01e-29: 120: 17.89
+	Hs
		964926 CUL1_HUMAN (18-768): 0: 709: 30.57		WDR5_HUMAN (96-410): 2.19e-56: 194: 15.04
+	Hs
		1115343 CUL4B_HUMAN (5-768): 0: 796: 36.77		FBXW7_HUMAN (448-544): 7.59e-15: 79.7: 17.53
+	At
		99584 CUL4_ARATH (8-768): 0: 748: 38.61		KTN82_ARATH (237-400): 1.27e-09: 63.2: 27.27
+	Mm
		1353853 CUL1_MOUSE (17-768): 0: 710: 30.53		FBXW7_MOUSE (448-544): 6.68e-15: 79.7: 17.53
+	Hs
		1112642 CUL1_HUMAN (18-768): 0: 709: 30.57		FBXW7_HUMAN (448-544): 7.59e-15: 79.7: 17.53