HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: WDR76 (Q9H967)
WD repeat-containing protein 76
Gene: WDR76

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25011449
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 626
+	Hs
		1115067 CUL4A_HUMAN (10-768): 0: 801: 38.32		WDR76_HUMAN (1-626): 5.23e-151: 451: 100.00
+	Hs
		1113760 CUL3_HUMAN (1-768): 0: 943: 100.00		COP1_HUMAN (154-619): 7.57e-71: 245: 14.96
+	Hs
		1114438 CUL3_HUMAN (1-768): 0: 943: 100.00		NLE1_HUMAN (181-575): 2.23e-63: 218: 12.47
+	Hs
		964927 CUL3_HUMAN (1-768): 0: 943: 100.00		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		209262 CUL3_HUMAN (1-768): 0: 943: 100.00		PRP4_HUMAN (401-624): 8.47e-40: 154: 15.09
+	Hs
		1113779 CUL3_HUMAN (1-768): 0: 943: 100.00		POC1B_HUMAN (435-626): 1.52e-36: 144: 12.95
+	Hs
		1114947 CUL4A_HUMAN (10-768): 0: 801: 38.32		COP1_HUMAN (154-619): 7.57e-71: 245: 14.96
+	Mm
		1189323 CUL4A_MOUSE (5-768): 0: 806: 37.81		COP1_MOUSE (154-619): 4.53e-68: 237: 14.58
+	Hs
		1114964 CUL4A_HUMAN (10-768): 0: 801: 38.32		DDB2_HUMAN (201-625): 2.11e-70: 235: 21.51
+	Hs
		1066294 CUL3_HUMAN (1-768): 0: 943: 100.00		RBBP4_HUMAN (233-477): 2.85e-19: 92.6: 14.55
+	Hs
		1098343 CUL4A_HUMAN (10-768): 0: 801: 38.32		ERCC8_HUMAN (305-532): 1.36e-57: 200: 19.92
+	Hs
		1114921 CUL4A_HUMAN (10-768): 0: 801: 38.32		WDR5B_HUMAN (395-624): 5.48e-51: 181: 11.74
+	Hs
		964928 CUL4A_HUMAN (10-768): 0: 801: 38.32		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		964929 CUL4B_HUMAN (5-768): 0: 796: 36.77		WDR5_HUMAN (435-622): 3.17e-42: 157: 12.23
+	Hs
		261407 CUL4B_HUMAN (5-768): 0: 796: 36.77		TBL1X_HUMAN (248-479): 5.35e-39: 153: 13.67
+	Hs
		1114950 CUL4A_HUMAN (10-768): 0: 801: 38.32		POC1B_HUMAN (435-626): 1.52e-36: 144: 12.95
+	Hs
		1114994 CUL4A_HUMAN (10-768): 0: 801: 38.32		SNR40_HUMAN (440-625): 1.14e-33: 134: 11.83
+	Hs
		1066295 CUL4A_HUMAN (10-768): 0: 801: 38.32		RBBP4_HUMAN (233-477): 2.85e-19: 92.6: 14.55
+	Hs
		845297 CUL4A_HUMAN (10-768): 0: 801: 38.32		LIS1_HUMAN (524-623): 3.63e-12: 70.5: 11.00
+	Hs
		845298 CUL4B_HUMAN (5-768): 0: 796: 36.77		LIS1_HUMAN (524-623): 3.63e-12: 70.5: 11.00