HitPredict

Interactor 1: SH21C (Q45HK4)
SH2 domain-containing protein 1B2 (EAT-2-related transducer) (ERT) (EAT-2B)
Gene: Sh2d1b2

Interactor 2: SLAF1 (Q9QUM4)
Signaling lymphocytic activation molecule (SLAM family member 1) (CD antigen CD150)
Gene: Slamf1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16425036
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 132 Mm			1 343
+	Mm
		1061798 Q149T1_MOUSE (1-132): 3.93e-41: 135: 83.33		SLAF1_MOUSE (1-343): 6.54e-96: 289: 100.00
+	Mm
		192617 SH21B_MOUSE (1-132): 1.62e-41: 135: 84.09		SLAF1_MOUSE (1-343): 6.54e-96: 289: 100.00
+	Mm
		763408 FYN_MOUSE (4-127): 1.31e-36: 132: 26.15		SLAF1_MOUSE (1-343): 6.54e-96: 289: 100.00
+	Mm
		1322348 SHIP1_MOUSE (4-132): 1e-34: 128: 30.23		SLAF1_MOUSE (1-343): 6.54e-96: 289: 100.00
+	Hs
		155840 SH21B_HUMAN (1-132): 2.75e-40: 132: 65.91		SLAF1_HUMAN (1-343): 4.59e-87: 267: 60.64
+	Hs
		412176 FYN_HUMAN (4-127): 1.51e-36: 132: 26.15		SLAF1_HUMAN (1-343): 4.59e-87: 267: 60.64
+	Hs
		1030743 SHIP1_HUMAN (5-132): 1.06e-34: 128: 28.91		SLAF1_HUMAN (1-343): 4.59e-87: 267: 60.64
+	Mm
		192616 SH21B_MOUSE (1-132): 1.62e-41: 135: 84.09		SLAF7_MOUSE (12-342): 4.12e-55: 185: 17.56
+	Hs
		411939 FYN_HUMAN (4-127): 1.51e-36: 132: 26.15		CD2_HUMAN (14-323): 1.55e-51: 176: 18.87
+	Hs
		155857 SH21B_HUMAN (1-132): 2.75e-40: 132: 65.91		SLAF7_HUMAN (5-342): 1.02e-50: 173: 17.89
+	Hs
		1271567 SHIP1_HUMAN (5-132): 1.06e-34: 128: 28.91		SLAF7_HUMAN (5-342): 1.02e-50: 173: 17.89
+	Hs
		155858 SH21B_HUMAN (1-132): 2.75e-40: 132: 65.91		SLAF5_HUMAN (12-339): 4.23e-47: 164: 20.46
+	Hs
		789096 ABL2_HUMAN (5-126): 3.99e-35: 129: 27.05		SLAF5_HUMAN (12-339): 4.23e-47: 164: 20.46
+	Hs
		155856 SH21B_HUMAN (1-132): 2.75e-40: 132: 65.91		CD244_HUMAN (32-339): 2.47e-45: 160: 20.25
+	Hs
		412347 FYN_HUMAN (4-127): 1.51e-36: 132: 26.15		CD244_HUMAN (32-339): 2.47e-45: 160: 20.25
+	Hs
		1271565 SHIP1_HUMAN (5-132): 1.06e-34: 128: 28.91		CD244_HUMAN (32-339): 2.47e-45: 160: 20.25
+	Mm
		991971 Q149T1_MOUSE (1-132): 3.93e-41: 135: 83.33		CD244_MOUSE (10-332): 2.42e-42: 153: 18.96
+	Hs
		155852 SH21B_HUMAN (1-132): 2.75e-40: 132: 65.91		SLAF6_HUMAN (13-338): 4.66e-42: 150: 19.88
+	Hs
		433317 YES_HUMAN (4-127): 2.82e-36: 131: 23.85		CXAR_HUMAN (10-339): 2.35e-41: 149: 13.74
+	Hs
		1271566 SHIP1_HUMAN (5-132): 1.06e-34: 128: 28.91		LY9_HUMAN (19-279): 8.14e-26: 110: 19.32